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pubmed-article:21631324pubmed:abstractTextStimulating an immune response against cancer with the use of vaccines remains a challenge. We hypothesized that combining a melanoma vaccine with interleukin-2, an immune activating agent, could improve outcomes. In a previous phase 2 study, patients with metastatic melanoma receiving high-dose interleukin-2 plus the gp100:209-217(210M) peptide vaccine had a higher rate of response than the rate that is expected among patients who are treated with interleukin-2 alone.lld:pubmed
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pubmed-article:21631324pubmed:articleTitlegp100 peptide vaccine and interleukin-2 in patients with advanced melanoma.lld:pubmed
pubmed-article:21631324pubmed:affiliationIndiana University Health Goshen Center for Cancer Care, Goshen, IN 46526, USA. dschwart@iuhealth.orglld:pubmed
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