| pubmed-article:21622982 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21622982 | lifeskim:mentions | umls-concept:C0015895 | lld:lifeskim |
| pubmed-article:21622982 | lifeskim:mentions | umls-concept:C0012737 | lld:lifeskim |
| pubmed-article:21622982 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:21622982 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:21622982 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:21622982 | pubmed:dateCreated | 2011-8-3 | lld:pubmed |
| pubmed-article:21622982 | pubmed:abstractText | The large post-reproductive life span reported for the free-living hermaphroditic nematode, Caenorhabditis elegans, which lives for about 10 days after its 5-day period of self-reproduction, seems at odds with evolutionary theory. Species with long post-reproductive life spans such as mammals are sometimes explained by a need for parental care or transfer of information. This does not seem a suitable explanation for C elegans. Previous reports have shown that C elegans can regain fertility when mated after the self-fertile period but did not report the functional limits. Here, we report the functional life span of the C elegans germ line when mating with males. We show that C elegans can regain fertility late in life (significantly later than in previous reports) and that the end of this period corresponds quite well to its 3-week total life span. Genetic analysis reveals that late-life fertility is controlled by conserved pathways involved with aging and dietary restriction. | lld:pubmed |
| pubmed-article:21622982 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21622982 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21622982 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:21622982 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21622982 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21622982 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:21622982 | pubmed:issn | 1758-535X | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:JohnsonThomas... | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:CypserJames... | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:PhillipsPatri... | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:LinkChristoph... | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:ParkSang-KyuS... | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:WuDeqingD | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:MendenhallAle... | lld:pubmed |
| pubmed-article:21622982 | pubmed:author | pubmed-author:TedescoPatric... | lld:pubmed |
| pubmed-article:21622982 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21622982 | pubmed:volume | 66 | lld:pubmed |
| pubmed-article:21622982 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21622982 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21622982 | pubmed:pagination | 842-54 | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:meshHeading | pubmed-meshheading:21622982... | lld:pubmed |
| pubmed-article:21622982 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21622982 | pubmed:articleTitle | Genetic dissection of late-life fertility in Caenorhabditis elegans. | lld:pubmed |
| pubmed-article:21622982 | pubmed:affiliation | Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80303, USA. alexander.mendenhall@colorado.edu | lld:pubmed |
| pubmed-article:21622982 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21622982 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:21622982 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
