| pubmed-article:2161212 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2161212 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:2161212 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:2161212 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2161212 | pubmed:dateCreated | 1990-7-5 | lld:pubmed |
| pubmed-article:2161212 | pubmed:abstractText | We have produced a monoclonal antibody that specifically recognizes the adrenocorticotropic receptor on rat adrenal cells. The immunogen was designed from an RNA sequence complementary to the mRNA coding for ACTH1-24. This complementary peptide, termed HTCA, has been shown to specifically bind ACTH and was proposed to mimic the ACTH binding site of the hormone receptor. The monoclonal anti-HTCA antibody recognized a restricted domain of the HTCA peptide, bound to Y-1 adrenal cells with a KD of 1.8 nM, and blocked the binding of 125I-ACTH to rat adrenal cells. These findings show that anti-HTCA competes with ACTH for binding to the ACTH receptor. | lld:pubmed |
| pubmed-article:2161212 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2161212 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2161212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2161212 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2161212 | pubmed:month | May | lld:pubmed |
| pubmed-article:2161212 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:2161212 | pubmed:author | pubmed-author:BostK LKL | lld:pubmed |
| pubmed-article:2161212 | pubmed:author | pubmed-author:ClarkeB LBL | lld:pubmed |
| pubmed-article:2161212 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2161212 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:2161212 | pubmed:volume | 168 | lld:pubmed |
| pubmed-article:2161212 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2161212 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2161212 | pubmed:pagination | 1020-6 | lld:pubmed |
| pubmed-article:2161212 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
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| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:meshHeading | pubmed-meshheading:2161212-... | lld:pubmed |
| pubmed-article:2161212 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2161212 | pubmed:articleTitle | A monoclonal anti-peptide antibody recognizes the adrenocorticotropic receptor. | lld:pubmed |
| pubmed-article:2161212 | pubmed:affiliation | University of Alabama, Department of Physiology and Biophysics, Birmingham. | lld:pubmed |
| pubmed-article:2161212 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2161212 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2161212 | lld:pubmed |
