Linked Life Data

21601258

Source:http://linkedlifedata.com/resource/pubmed/id/21601258

Statements in which the resource exists.
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pubmed-article:21601258pubmed:abstractTextCancer cells in the body release soluble and membranous factors that manipulate the tumor environment to facilitate growth and survival. Recent years have provided evidence that small microvesicles that are termed exosomes may play a pivotal role in this process. Exosomes are membrane vesicles with a size of 40-100 nm that are released by both tumor and normal cells and can be found in various body fluids. Tumor-derived exosomes carry functional proteins, mRNAs, and miRNAs and could serve as novel platform for tumor diagnosis and prognosis. However, marker proteins that allow enrichment of tumor-derived exosomes over normal exosomes are less well defined.lld:pubmed
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pubmed-article:21601258pubmed:copyrightInfoCopyright © 2011 Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:21601258pubmed:volume122lld:pubmed
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pubmed-article:21601258pubmed:dateRevised2011-10-28lld:pubmed
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pubmed-article:21601258pubmed:articleTitleLoss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage.lld:pubmed
pubmed-article:21601258pubmed:affiliationTumor Immunology Programme, D015, German Cancer Research Center, D-69120 Heidelberg, Germany.lld:pubmed
pubmed-article:21601258pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21601258pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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