| pubmed-article:21584812 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21584812 | lifeskim:mentions | umls-concept:C0021083 | lld:lifeskim |
| pubmed-article:21584812 | lifeskim:mentions | umls-concept:C0376545 | lld:lifeskim |
| pubmed-article:21584812 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:21584812 | pubmed:dateCreated | 2011-6-24 | lld:pubmed |
| pubmed-article:21584812 | pubmed:abstractText | Many hematological malignancies consist of tumor cells that are spontaneously recognized and killed by V?9V?2 T cells. These tumor cells generate high amounts of intracellular phosphorylated metabolites mimicking the natural ligands and display a wide range of stress-induced self-ligands that are recognized by V?9V?2 T cells via TCR-dependent and TCR-independent mechanisms. The intrinsic features of V?9V?2 T cells and that of tumor cells of hematological origin constitute an ideal combination from which to develop V?9V?2 T cell-based immune interventions. In this review, we will discuss the rationale, preclinical and clinical data in favor of this therapeutic strategy and the future perspectives of its development. | lld:pubmed |
| pubmed-article:21584812 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21584812 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21584812 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21584812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21584812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21584812 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21584812 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21584812 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:21584812 | pubmed:issn | 1420-9071 | lld:pubmed |
| pubmed-article:21584812 | pubmed:author | pubmed-author:KIMU HUH | lld:pubmed |
| pubmed-article:21584812 | pubmed:author | pubmed-author:CosciaMartaM | lld:pubmed |
| pubmed-article:21584812 | pubmed:author | pubmed-author:CastellaBarba... | lld:pubmed |
| pubmed-article:21584812 | pubmed:author | pubmed-author:VitaleCandida... | lld:pubmed |
| pubmed-article:21584812 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21584812 | pubmed:volume | 68 | lld:pubmed |
| pubmed-article:21584812 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21584812 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21584812 | pubmed:pagination | 2419-32 | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:meshHeading | pubmed-meshheading:21584812... | lld:pubmed |
| pubmed-article:21584812 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21584812 | pubmed:articleTitle | V?9V?2 T cell-based immunotherapy in hematological malignancies: from bench to bedside. | lld:pubmed |
| pubmed-article:21584812 | pubmed:affiliation | Laboratorio di Ematologia Oncologica, Centro di Ricerca in Medicina Sperimentale (CeRMS), and Divisione Universitaria di Ematologia, Ospedale San Giovanni Battista di Torino e Universita' degli Studi di Torino, Turin, Italy. | lld:pubmed |
| pubmed-article:21584812 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21584812 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:21584812 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
