Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:21562016rdf:typepubmed:Citationlld:pubmed
pubmed-article:21562016lifeskim:mentionsumls-concept:C1123023lld:lifeskim
pubmed-article:21562016lifeskim:mentionsumls-concept:C0024141lld:lifeskim
pubmed-article:21562016lifeskim:mentionsumls-concept:C0017262lld:lifeskim
pubmed-article:21562016lifeskim:mentionsumls-concept:C2911684lld:lifeskim
pubmed-article:21562016lifeskim:mentionsumls-concept:C0185117lld:lifeskim
pubmed-article:21562016pubmed:issue9lld:pubmed
pubmed-article:21562016pubmed:dateCreated2011-7-12lld:pubmed
pubmed-article:21562016pubmed:abstractTextThe objective of this study was to investigate the expression and relationship of LL-37, plasmacytoid dendritic cells (pDCs) and interferon-alpha (IFN-?) in skin in systemic lupus erythematosus (SLE), and their role in SLE pathogenesis. Skin biopsies were taken from nine SLE patients and six healthy volunteers. Expression of LL-37, pDCs and IFN-? in skin specimens and consecutive sections of skin was detected with an immunohistochemical technique (IH); the expression of LL-37 and pDCs in the samples was detected with in situ hybridization (ISH). The expression levels of LL-37, pDCs and IFN-? were significantly higher in SLE skin than in that of healthy controls (p?<?0.001) with either the IH or the ISH technique, and the location of positive expression in consecutive sections was similar. Correlation analysis showed that the expression levels of LL-37, pDCs and IFN-? correlated positively with each other. In conclusion, the expression of LL-37, pDCs and IFN-? was increased in the skin of patients with active SLE. It is necessary to study further the role of LL-37 in the pathogenesis of SLE, and the exact relationship among LL-37, pDCs and IFN-?.lld:pubmed
pubmed-article:21562016pubmed:languageenglld:pubmed
pubmed-article:21562016pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21562016pubmed:citationSubsetIMlld:pubmed
pubmed-article:21562016pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21562016pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21562016pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21562016pubmed:statusMEDLINElld:pubmed
pubmed-article:21562016pubmed:monthAuglld:pubmed
pubmed-article:21562016pubmed:issn1477-0962lld:pubmed
pubmed-article:21562016pubmed:authorpubmed-author:LiPPlld:pubmed
pubmed-article:21562016pubmed:authorpubmed-author:LotFFlld:pubmed
pubmed-article:21562016pubmed:authorpubmed-author:SunC-LCLlld:pubmed
pubmed-article:21562016pubmed:authorpubmed-author:ZhangF-ZFZlld:pubmed
pubmed-article:21562016pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21562016pubmed:volume20lld:pubmed
pubmed-article:21562016pubmed:ownerNLMlld:pubmed
pubmed-article:21562016pubmed:authorsCompleteYlld:pubmed
pubmed-article:21562016pubmed:pagination904-11lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:meshHeadingpubmed-meshheading:21562016...lld:pubmed
pubmed-article:21562016pubmed:year2011lld:pubmed
pubmed-article:21562016pubmed:articleTitleLL-37 expression in the skin in systemic lupus erythematosus.lld:pubmed
pubmed-article:21562016pubmed:affiliationDepartment of Rheumatology and Immunology, China-Japan Union Hospital of Jilin University, Changchun, China.lld:pubmed
pubmed-article:21562016pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21562016pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:820entrezgene:pubmedpubmed-article:21562016lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:21562016lld:entrezgene