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pubmed-article:21549957pubmed:issue9lld:pubmed
pubmed-article:21549957pubmed:dateCreated2011-5-9lld:pubmed
pubmed-article:21549957pubmed:abstractTextThe plant hormone abscisic acid (ABA) mediates seed dormancy, controls seedling development and triggers tolerance to abiotic stresses, including drought. Core ABA signaling components consist of a recently identified group of ABA receptor proteins of the PYRABACTIN RESISTANCE (PYR)/REGULATORY COMPONENT OF ABA RECEPTOR (RCAR) family that act as negative regulators of members of the PROTEIN PHOSPHATASE 2C (PP2C) family. Inhibition of PP2C activity enables activation of SNF1-RELATED KINASE 2 (SnRK2) protein kinases, which target downstream components, including transcription factors, ion channels and NADPH oxidases. These and other components form a complex ABA signaling network. Here, an in depth analysis of the evolution of components in this ABA signaling network shows that (i) PYR/RCAR ABA receptor and ABF-type transcription factor families arose during land colonization of plants and are not found in algae and other species, (ii) ABA biosynthesis enzymes have evolved to plant- and fungal-specific forms, leading to different ABA synthesis pathways, (iii) existing stress signaling components, including PP2C phosphatases and SnRK kinases, were adapted for novel roles in this plant-specific network to respond to water limitation. In addition, evolutionarily conserved secondary structures in the PYR/RCAR ABA receptor family are visualized.lld:pubmed
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pubmed-article:21549957pubmed:statusMEDLINElld:pubmed
pubmed-article:21549957pubmed:monthMaylld:pubmed
pubmed-article:21549957pubmed:issn1879-0445lld:pubmed
pubmed-article:21549957pubmed:authorpubmed-author:SchroederJuli...lld:pubmed
pubmed-article:21549957pubmed:authorpubmed-author:HauserFelixFlld:pubmed
pubmed-article:21549957pubmed:authorpubmed-author:WaadtRainerRlld:pubmed
pubmed-article:21549957pubmed:copyrightInfoCopyright © 2011 Elsevier Ltd. All rights reserved.lld:pubmed
pubmed-article:21549957pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21549957pubmed:day10lld:pubmed
pubmed-article:21549957pubmed:volume21lld:pubmed
pubmed-article:21549957pubmed:ownerNLMlld:pubmed
pubmed-article:21549957pubmed:authorsCompleteYlld:pubmed
pubmed-article:21549957pubmed:paginationR346-55lld:pubmed
pubmed-article:21549957pubmed:dateRevised2011-9-26lld:pubmed
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pubmed-article:21549957pubmed:year2011lld:pubmed
pubmed-article:21549957pubmed:articleTitleEvolution of abscisic acid synthesis and signaling mechanisms.lld:pubmed
pubmed-article:21549957pubmed:affiliationDivision of Biological Sciences, Cell and Developmental Biology Section, University of California San Diego, La Jolla, CA 92093-0116, USA.lld:pubmed
pubmed-article:21549957pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21549957pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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pubmed-article:21549957pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:21549957pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed
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