| pubmed-article:2154154 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C0024109 | lld:lifeskim |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C0178602 | lld:lifeskim |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C0011209 | lld:lifeskim |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C1112870 | lld:lifeskim |
| pubmed-article:2154154 | lifeskim:mentions | umls-concept:C0336862 | lld:lifeskim |
| pubmed-article:2154154 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2154154 | pubmed:dateCreated | 1990-3-15 | lld:pubmed |
| pubmed-article:2154154 | pubmed:abstractText | The purpose of this study was to compare deposition of aerosol to the lung from a metered-dose inhaler (MDI) and aerosol holding chamber and from a jet nebulizer in ventilator-dependent patients. Twenty-one patients were entered into the study, all receiving assisted ventilation and inhaled bronchodilators because of airflow limitation. The average age was 68 yr; there were 10 men and 11 women. The patients were randomized to receive either 4 puffs (800 micrograms) of radiolabeled fenoterol by MDI of 1.75 ml (1,750 micrograms) of radiolabeled fenoterol solution by nebulizer. Imaging of lung fields was made by a portable scintillation camera at 5-min intervals during the study. Results showed that 20 patients completed the study, 9 receiving fenoterol by MDI, and 11 by jet nebulizer. Four were excluded from analysis because of previous pneumonectomy, two from each group. Lung deposition measured as a percent of given dose from either system was 5.65 +/- 1.09 (mean +/- SEM) for MDI plus extension chamber and 1.22 +/- 0.35 for jet nebulizer (p less than 0.001). Therefore, this trial shows significantly greater efficiency of aerosol deposition to the lung in ventilator-dependent patients when using an MDI plus aerosol holding chamber than when using a jet nebulizer. | lld:pubmed |
| pubmed-article:2154154 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2154154 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154154 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:2154154 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2154154 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2154154 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2154154 | pubmed:issn | 0003-0805 | lld:pubmed |
| pubmed-article:2154154 | pubmed:author | pubmed-author:NewhouseM TMT | lld:pubmed |
| pubmed-article:2154154 | pubmed:author | pubmed-author:DolovichM BMB | lld:pubmed |
| pubmed-article:2154154 | pubmed:author | pubmed-author:FullerH DHD | lld:pubmed |
| pubmed-article:2154154 | pubmed:author | pubmed-author:PosmituckGG | lld:pubmed |
| pubmed-article:2154154 | pubmed:author | pubmed-author:PackW WWW | lld:pubmed |
| pubmed-article:2154154 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2154154 | pubmed:volume | 141 | lld:pubmed |
| pubmed-article:2154154 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2154154 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2154154 | pubmed:pagination | 440-4 | lld:pubmed |
| pubmed-article:2154154 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:2154154 | pubmed:meshHeading | pubmed-meshheading:2154154-... | lld:pubmed |
| pubmed-article:2154154 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2154154 | pubmed:articleTitle | Pressurized aerosol versus jet aerosol delivery to mechanically ventilated patients. Comparison of dose to the lungs. | lld:pubmed |
| pubmed-article:2154154 | pubmed:affiliation | Department of Medicine, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada. | lld:pubmed |
| pubmed-article:2154154 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2154154 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2154154 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2154154 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:2154154 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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