| pubmed-article:21529352 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21529352 | lifeskim:mentions | umls-concept:C1522449 | lld:lifeskim |
| pubmed-article:21529352 | lifeskim:mentions | umls-concept:C0029463 | lld:lifeskim |
| pubmed-article:21529352 | lifeskim:mentions | umls-concept:C0021467 | lld:lifeskim |
| pubmed-article:21529352 | lifeskim:mentions | umls-concept:C1421500 | lld:lifeskim |
| pubmed-article:21529352 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:21529352 | pubmed:dateCreated | 2011-5-30 | lld:pubmed |
| pubmed-article:21529352 | pubmed:abstractText | The use of radiotherapy in osteosarcoma (OS) is controversial due to its radioresistance. OS patients currently treated with radiotherapy generally are inoperable, have painful skeletal metastases, refuse surgery or have undergone an intralesional resection of the primary tumor. After irradiation-induced DNA damage, OS cells sustain a prolonged G(2) cell cycle checkpoint arrest allowing DNA repair and evasion of cell death. Inhibition of WEE1 kinase leads to abrogation of the G(2) arrest and could sensitize OS cells to irradiation induced cell death. | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21529352 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21529352 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21529352 | pubmed:issn | 1471-2407 | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:KaspersGertja... | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:HelderMarco... | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:van... | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:GraatHarm C... | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:WürdingerThom... | lld:pubmed |
| pubmed-article:21529352 | pubmed:author | pubmed-author:PosthumaDeBoe... | lld:pubmed |
| pubmed-article:21529352 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21529352 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:21529352 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21529352 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21529352 | pubmed:pagination | 156 | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:meshHeading | pubmed-meshheading:21529352... | lld:pubmed |
| pubmed-article:21529352 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21529352 | pubmed:articleTitle | WEE1 inhibition sensitizes osteosarcoma to radiotherapy. | lld:pubmed |
| pubmed-article:21529352 | pubmed:affiliation | Department of Orthopaedic Surgery, VU University Medical Center, 1007 MB Amsterdam, the Netherlands. | lld:pubmed |
| pubmed-article:21529352 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21529352 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:7465 | entrezgene:pubmed | pubmed-article:21529352 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21529352 | lld:entrezgene |
