| pubmed-article:2150599 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0087140 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0029005 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0080294 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0085943 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0086860 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0013879 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:2150599 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:2150599 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2150599 | pubmed:dateCreated | 1991-5-16 | lld:pubmed |
| pubmed-article:2150599 | pubmed:abstractText | The Mos protein is a serine/threonine protein kinase that is likely to be a part of signal transduction pathways that regulate cell growth. We show here that expression of the v-Mos protein leads to a transient transcriptional activation of the c-fos and the c-jun proto-oncogenes in NIH 3T3 cells. Different cis-acting promoter elements are responsible for this effect. In the c-fos promoter the dyad symmetry element (DSE, also known as serum response element, SRE) is sufficient to confer responsiveness to the v-Mos protein. In the c-jun promoter the 12-0-tetradecanoyl-phorbol-13-acetate (TPA) response element (TRE) mediates this effect. Various Mos mutants with decreased transforming activity have diminished trans-acting activity on the c-fos and c-jun promoters. These results suggest that the highly transforming v-Mos protein exerts at least some of its effects through the induction of expression of the c-fos and c-jun protooncogenes. | lld:pubmed |
| pubmed-article:2150599 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2150599 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2150599 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2150599 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2150599 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2150599 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2150599 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2150599 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2150599 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2150599 | pubmed:issn | 1043-4674 | lld:pubmed |
| pubmed-article:2150599 | pubmed:author | pubmed-author:FeramiscoJ... | lld:pubmed |
| pubmed-article:2150599 | pubmed:author | pubmed-author:SchönthalAA | lld:pubmed |
| pubmed-article:2150599 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2150599 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:2150599 | pubmed:geneSymbol | c-fos | lld:pubmed |
| pubmed-article:2150599 | pubmed:geneSymbol | c-jun | lld:pubmed |
| pubmed-article:2150599 | pubmed:geneSymbol | v-mos | lld:pubmed |
| pubmed-article:2150599 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2150599 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2150599 | pubmed:pagination | 143-50 | lld:pubmed |
| pubmed-article:2150599 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:meshHeading | pubmed-meshheading:2150599-... | lld:pubmed |
| pubmed-article:2150599 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2150599 | pubmed:articleTitle | Different promoter elements are required for the induced expression of c-fos and c-jun proto-oncogenes by the v-mos oncogene product. | lld:pubmed |
| pubmed-article:2150599 | pubmed:affiliation | Department of Medicine, University of California, San Diego, La Jolla 92093. | lld:pubmed |
| pubmed-article:2150599 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2150599 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2150599 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2150599 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2150599 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2150599 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2150599 | lld:pubmed |
