| pubmed-article:21501635 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C1261473 | lld:lifeskim |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C0599773 | lld:lifeskim |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C2699123 | lld:lifeskim |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C1419240 | lld:lifeskim |
| pubmed-article:21501635 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
| pubmed-article:21501635 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21501635 | pubmed:dateCreated | 2011-5-30 | lld:pubmed |
| pubmed-article:21501635 | pubmed:abstractText | RAD51 and RAD54, members of the RAD52 epistasis group, play key roles in homologous recombination (HR). The efficiency of homologous recombination (HR) can be increased by over-expression of either of them. A vector that allows co-expression of RAD51 and RAD54 was constructed to investigate interactions between the two proteins during extra-chromosomal HR. The efficiency of extra-chromosomal HR evaluated by GFP extra-chromosomal HR was enhanced (110-245%) in different transfected Human sarcoma (HT-1080) cell colonies. We observed that RAD51 clearly promotes extra-chromosomal HR; however, the actions of RAD54 in extra-chromosomal HR were weak. Our data suggest that RAD51 may function as a universal factor during HR, whereas RAD54 mainly functions in other types of HR (gene targeting or intra-chromosomal HR), which involves interaction with chromosomal DNA. | lld:pubmed |
| pubmed-article:21501635 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21501635 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21501635 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21501635 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21501635 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21501635 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21501635 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21501635 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21501635 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:21501635 | pubmed:issn | 1873-4863 | lld:pubmed |
| pubmed-article:21501635 | pubmed:author | pubmed-author:LiNingN | lld:pubmed |
| pubmed-article:21501635 | pubmed:author | pubmed-author:DaiYunpingY | lld:pubmed |
| pubmed-article:21501635 | pubmed:author | pubmed-author:SongZhiyuanZ | lld:pubmed |
| pubmed-article:21501635 | pubmed:author | pubmed-author:LuoJunjieJ | lld:pubmed |
| pubmed-article:21501635 | pubmed:author | pubmed-author:YuShengliS | lld:pubmed |
| pubmed-article:21501635 | pubmed:copyrightInfo | Published by Elsevier B.V. | lld:pubmed |
| pubmed-article:21501635 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21501635 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:21501635 | pubmed:volume | 154 | lld:pubmed |
| pubmed-article:21501635 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21501635 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21501635 | pubmed:pagination | 21-4 | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:meshHeading | pubmed-meshheading:21501635... | lld:pubmed |
| pubmed-article:21501635 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21501635 | pubmed:articleTitle | Over-expression of RAD51 or RAD54 but not RAD51/4 enhances extra-chromosomal homologous recombination in the human sarcoma (HT-1080) cell line. | lld:pubmed |
| pubmed-article:21501635 | pubmed:affiliation | State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, People's Republic of China. victory811111@126.com | lld:pubmed |
| pubmed-article:21501635 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21501635 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:5888 | entrezgene:pubmed | pubmed-article:21501635 | lld:entrezgene |
| entrez-gene:546 | entrezgene:pubmed | pubmed-article:21501635 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21501635 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21501635 | lld:entrezgene |
