pubmed-article:21500882 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C0035804 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C0424295 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C0036849 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C1442518 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C1552652 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C1552685 | lld:lifeskim |
pubmed-article:21500882 | lifeskim:mentions | umls-concept:C1705195 | lld:lifeskim |
pubmed-article:21500882 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:21500882 | pubmed:dateCreated | 2011-6-6 | lld:pubmed |
pubmed-article:21500882 | pubmed:abstractText | Two experiments compared spontaneously hypertensive rats (SHRs; a rodent model of attention-deficit/hyperactivity disorder) and Wistar rats (a normoactive control strain), on the acquisition of a set-shifting strategy. In Experiment 1, SHRs and Wistar rats were equivalent in trials to criterion to learn a brightness or a texture discrimination but SHRs were faster than Wistar rats in shifting to the opposite discrimination when there was 1 or 2 days between the initial discrimination and the shift. In Experiment 2, SHRs and Wistar rats were equivalent in shifting when the shift between discriminations occurred immediately after a criterion had been met in the first discrimination. The results are discussed in terms of a failure of SHRs to store or retrieve an initial discrimination and/or latent inhibition over a delay, leading to faster acquisition of a set-shift. This failure in storage or retrieval may be the result of a hypoactive dopamine system in the prefrontal cortex and nucleus accumbens shell as well as abnormalities in entorhinal cortex in SHRs. | lld:pubmed |
pubmed-article:21500882 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21500882 | pubmed:language | eng | lld:pubmed |
pubmed-article:21500882 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21500882 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:21500882 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:21500882 | pubmed:month | Jun | lld:pubmed |
pubmed-article:21500882 | pubmed:issn | 1939-0084 | lld:pubmed |
pubmed-article:21500882 | pubmed:author | pubmed-author:GreenJohn TJT | lld:pubmed |
pubmed-article:21500882 | pubmed:author | pubmed-author:StefaniMark... | lld:pubmed |
pubmed-article:21500882 | pubmed:author | pubmed-author:ChessAmy CAC | lld:pubmed |
pubmed-article:21500882 | pubmed:author | pubmed-author:RaymondBritta... | lld:pubmed |
pubmed-article:21500882 | pubmed:author | pubmed-author:Gardner-Morse... | lld:pubmed |
pubmed-article:21500882 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:21500882 | pubmed:volume | 125 | lld:pubmed |
pubmed-article:21500882 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:21500882 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:21500882 | pubmed:pagination | 372-82 | lld:pubmed |
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pubmed-article:21500882 | pubmed:year | 2011 | lld:pubmed |
pubmed-article:21500882 | pubmed:articleTitle | Set shifting in a rodent model of attention-deficit/hyperactivity disorder. | lld:pubmed |
pubmed-article:21500882 | pubmed:affiliation | Department of Psychology, Champlain College. | lld:pubmed |
pubmed-article:21500882 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:21500882 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:21500882 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |