| pubmed-article:21487493 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21487493 | lifeskim:mentions | umls-concept:C0024554 | lld:lifeskim |
| pubmed-article:21487493 | lifeskim:mentions | umls-concept:C0337664 | lld:lifeskim |
| pubmed-article:21487493 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:21487493 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:21487493 | lifeskim:mentions | umls-concept:C1515075 | lld:lifeskim |
| pubmed-article:21487493 | lifeskim:mentions | umls-concept:C0332173 | lld:lifeskim |
| pubmed-article:21487493 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21487493 | pubmed:dateCreated | 2011-4-13 | lld:pubmed |
| pubmed-article:21487493 | pubmed:abstractText | Limited information from human studies indicates that dietary quercetin supplementation influences blood lipid profiles, glycemic response, and inflammatory status, collectively termed cardiometabolic risks. We tested the hypothesis that quercetin-rich supplementation, derived from onion peel extract, improves cardiometabolic risk components in healthy male smokers in a randomized, double blinded, placebo-controlled parallel design. Randomly assigned subjects were instructed to take either the placebo (n = 43) or 100 mg quercetin capsules each day (n = 49) for 10 weeks. Anthropometric parameters and blood pressure were measured, and blood lipids, glucose, interleukin-6, and soluble vascular cell adhesion molecule-1 (sVCAM-1) were determined at baseline and after 10 weeks of quercetin supplementation. Quercetin-rich supplementation significantly reduced serum concentrations of total cholesterol (P < 0.05) and LDL-cholesterol (P < 0.01), whereas these effects were not shown in the placebo group. Furthermore, significant increases were observed in serum concentrations of HDL-cholesterol both in the placebo (P < 0.005) and quercetin-rich supplementation group (P < 0.001); however, changes in HDL-cholesterol were significantly greater in subjects receiving quercetin-rich supplementation than the placebo. Both systolic (P < 0.05) and diastolic blood pressure (P < 0.01) decreased significantly in the quercetin-rich supplementation group. Glucose concentrations decreased significantly after 10 weeks of quercetin-rich supplementation (P < 0.05). In contrast, no effects of quercetin-rich supplementation were observed for the inflammatory markers-IL-6 and sVCAM-1. Daily quercetin-rich supplementation from onion peel extract improved blood lipid profiles, glucose, and blood pressure, suggesting a beneficial role for quercetin as a preventive measure against cardiovascular risk. | lld:pubmed |
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| pubmed-article:21487493 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21487493 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21487493 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
| pubmed-article:21487493 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:21487493 | pubmed:issn | 2005-6168 | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:KimMyeong-OkM... | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:LeeHyeranH | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:ParkEunjuE | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:LeeHye-JinHJ | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:ShinMin-Jeong... | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:ChaYong-JunYJ | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:KimJung-MiJM | lld:pubmed |
| pubmed-article:21487493 | pubmed:author | pubmed-author:LeeKyung-HeaK... | lld:pubmed |
| pubmed-article:21487493 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21487493 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:21487493 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21487493 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21487493 | pubmed:pagination | 28-33 | lld:pubmed |
| pubmed-article:21487493 | pubmed:dateRevised | 2011-7-28 | lld:pubmed |
| pubmed-article:21487493 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21487493 | pubmed:articleTitle | Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers. | lld:pubmed |
| pubmed-article:21487493 | pubmed:affiliation | Department of Food and Nutrition, Changwon National University, Gyeongnam 641-773, Korea. | lld:pubmed |
| pubmed-article:21487493 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:21487493 | lld:pubmed |
