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pubmed-article:2148476pubmed:abstractTextMode of the expression of phosphofructokinase (PFK) -M and -L genes was examined in various human tissues including muscle, placenta, liver, kidney, pancreas, stomach and reticulocytes. The gross level of mRNA expression of PFK-M and -L genes was estimated by Northern analysis. Polymerase chain reaction was used to detect mRNA expressed at low levels in these tissues. Tissue-specific expression of alternatively spliced PFK-M gene transcripts was also determined by polymerase chain reaction. The results indicated that alternative splicing of PFK-M gene transcripts was controlled in a tissue-specific manner.lld:pubmed
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pubmed-article:2148476pubmed:articleTitleTissue specificity in expression and alternative RNA splicing of human phosphofructokinase-M and -L genes.lld:pubmed
pubmed-article:2148476pubmed:affiliationSecond Department of Internal Medicine, Osaka University Medical School, Japan.lld:pubmed
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