| pubmed-article:2147706 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0155626 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0021308 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0424295 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0206146 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0080310 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0303611 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0456389 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C0035124 | lld:lifeskim |
| pubmed-article:2147706 | lifeskim:mentions | umls-concept:C1881865 | lld:lifeskim |
| pubmed-article:2147706 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:2147706 | pubmed:dateCreated | 1991-1-24 | lld:pubmed |
| pubmed-article:2147706 | pubmed:abstractText | Quantitation of perfusion defect size using tomographic imaging with technetium-99m-hexakis-2-methoxy isobutyl isonitrile was performed at the time of hospital discharge in 32 patients with a first myocardial infarction who underwent successful coronary reperfusion within 8 h of the onset of chest pain. Reperfusion was accomplished with thrombolysis or primary coronary angioplasty. Radionuclide angiography was performed at discharge and 6 weeks later. There was a close correlation between perfusion defect size and values for ejection fraction and regional wall motion both at discharge (r = -0.80 and -0.75, respectively) and 6 weeks later (r = -0.81 and -0.81, respectively). There was no overall group difference in ejection fraction between the value at discharge and at 6 weeks; however, five patients had a significant increase (greater than or equal to 0.08) and six had a significant decrease (greater than or equal to 0.08) in ejection fraction. In patients with a significant increase at 6 weeks, ejection fraction was significantly lower at discharge than the value predicted from perfusion defect size (0.37 +/- 0.09 measured versus 0.47 +/- 0.13 predicted, p less than 0.05) and it improved at 6 weeks to near predicted values (0.51 +/- 0.07). In patients with a significant decrease at 6 weeks, ejection fraction was significantly higher at discharge than the value predicted from perfusion defect size (0.60 +/- 0.10 measured versus 0.50 +/- 0.10 predicted, p less than 0.05) and it decreased at 6 weeks to near predicted levels (0.51 +/- 0.09). Left ventricular ejection fraction at the time of hospital discharge is a potentially misleading index of the efficacy of reperfusion therapy for myocardial infarction. In a significant minority (34%) of patients this index does not accurately reflect perfusion defect size, apparently because of the effects of myocardial stunning and compensatory hyperkinesia. | lld:pubmed |
| pubmed-article:2147706 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2147706 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2147706 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2147706 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:2147706 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2147706 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2147706 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2147706 | pubmed:issn | 0735-1097 | lld:pubmed |
| pubmed-article:2147706 | pubmed:author | pubmed-author:GibbonsR JRJ | lld:pubmed |
| pubmed-article:2147706 | pubmed:author | pubmed-author:ChesebroJ HJH | lld:pubmed |
| pubmed-article:2147706 | pubmed:author | pubmed-author:PellikkaP APA | lld:pubmed |
| pubmed-article:2147706 | pubmed:author | pubmed-author:ChristianT... | lld:pubmed |
| pubmed-article:2147706 | pubmed:author | pubmed-author:BehrenbeckTT | lld:pubmed |
| pubmed-article:2147706 | pubmed:author | pubmed-author:HuberK CKC | lld:pubmed |
| pubmed-article:2147706 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2147706 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:2147706 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2147706 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2147706 | pubmed:pagination | 1632-8 | lld:pubmed |
| pubmed-article:2147706 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2147706 | pubmed:meshHeading | pubmed-meshheading:2147706-... | lld:pubmed |
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| pubmed-article:2147706 | pubmed:meshHeading | pubmed-meshheading:2147706-... | lld:pubmed |
| pubmed-article:2147706 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2147706 | pubmed:articleTitle | Mismatch of left ventricular function and infarct size demonstrated by technetium-99m isonitrile imaging after reperfusion therapy for acute myocardial infarction: identification of myocardial stunning and hyperkinesia. | lld:pubmed |
| pubmed-article:2147706 | pubmed:affiliation | Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905. | lld:pubmed |
| pubmed-article:2147706 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2147706 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2147706 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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