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pubmed-article:21462042pubmed:abstractTextPhytochemical investigation of the leaf of Ilex centrochinensis led to the isolation and characterization of four flavans, one flavanone (5), and one flavone (6), including a new compound whose structure was elucidated as (2S)-5,3',4'-trihydroxy-7-methoxyflavan (1) and a new natural product whose structure was elucidated as (2S)-5-hydroxy-7,3',4'-trimethoxyflavan (4) on the basis of spectroscopic methods especially 1D and 2D NMR, CD, and mass spectral analyses. Compounds 1 and 4 exhibited weak cytotoxic activity against Huh7 cell line and no cytotoxic activity against Caco-2 cell line.lld:pubmed
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pubmed-article:21462042pubmed:authorpubmed-author:ZhangYueYlld:pubmed
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pubmed-article:21462042pubmed:authorpubmed-author:LiLu-JunLJlld:pubmed
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pubmed-article:21462042pubmed:year2011lld:pubmed
pubmed-article:21462042pubmed:articleTitleFlavans from the leaf of Ilex centrochinensis.lld:pubmed
pubmed-article:21462042pubmed:affiliationHubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji School of Pharmaceutical Sciences, Huazhong University of Science and Technology, Wuhan, China.lld:pubmed
pubmed-article:21462042pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21462042pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed