Mislocalization of the E3 ligase, ?-transducin repeat-containing protein 1 (?-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.

Source:http://linkedlifedata.com/resource/pubmed/id/21454620

J. Biol. Chem. 2011 Jun 3 286 22 19777-88

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21454620