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pubmed-article:21429799pubmed:abstractTextVascular endothelial growth factor (VEGF) has a crucial role in angiogenesis, and is a valid target in metastatic breast cancer. Motesanib is an investigational oral inhibitor of VEGF receptors. We aimed to determine whether treatment with motesanib plus paclitaxel is better than placebo plus paclitaxel in patients with HER2-negative locally recurrent or metastatic breast cancer.lld:pubmed
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pubmed-article:21429799pubmed:copyrightInfoCopyright © 2011 Elsevier Ltd. All rights reserved.lld:pubmed
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pubmed-article:21429799pubmed:articleTitleMotesanib, or open-label bevacizumab, in combination with paclitaxel, as first-line treatment for HER2-negative locally recurrent or metastatic breast cancer: a phase 2, randomised, double-blind, placebo-controlled study.lld:pubmed
pubmed-article:21429799pubmed:affiliationGrupo Español de Investigación en Cáncer de Mama, Madrid, Spain. mmartin@geicam.orglld:pubmed
pubmed-article:21429799pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21429799pubmed:publicationTypeRandomized Controlled Triallld:pubmed
pubmed-article:21429799pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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