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pubmed-article:2142143pubmed:abstractTextPlasma atrial natriuretic peptide was measured in 10 children undergoing the Fontan procedure and 3 children undergoing total cavopulmonary connexion. There was no significant difference in pre-operative plasma levels, but post-operative levels were significantly higher 48 hours after cardiopulmonary bypass in the Fontan group. There was no significant difference in plasma arginine vasopressin levels either pre- or post-operatively. Post-operative pleural effusions occurred in only 2 of the 10 patients undergoing the Fontan procedure, but were present in all 3 of those undergoing total cavopulmonary connexion. The release of atrial natriuretic peptide is an appropriate homeostatic response to volume loading and the impairment of this response in the early post-operative period may be of clinical importance.lld:pubmed
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pubmed-article:2142143pubmed:articleTitlePlasma atrial natriuretic peptide after the Fontan procedure and total cavopulmonary connexion.lld:pubmed
pubmed-article:2142143pubmed:affiliationBrompton Hospital, London, U.K.lld:pubmed
pubmed-article:2142143pubmed:publicationTypeJournal Articlelld:pubmed
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