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pubmed-article:21415394pubmed:abstractTextThe cytosolic protease calpain has been recently implicated in the vascular remodeling of angiotensin II (Ang II) type 1 receptor (AT(1)R) signaling. The role of Ang II/AT(1)R/calpain signaling on endothelial function, an important and early determinant of vascular pathology, remains though totally unknown. Accordingly, we investigated the role of calpain in the endothelial dysfunction of Ang II.lld:pubmed
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pubmed-article:21415394pubmed:articleTitleA novel role for calpain in the endothelial dysfunction induced by activation of angiotensin II type 1 receptor signaling.lld:pubmed
pubmed-article:21415394pubmed:affiliationDepartment of Physiology, and The Cardiovascular Research Center, Temple University, Philadelphia, PA 19140, USA. rscalia@temple.edulld:pubmed
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