| pubmed-article:2141470 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0003261 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0733755 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0150305 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C1561964 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0872192 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:2141470 | lifeskim:mentions | umls-concept:C0205345 | lld:lifeskim |
| pubmed-article:2141470 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2141470 | pubmed:dateCreated | 1990-7-26 | lld:pubmed |
| pubmed-article:2141470 | pubmed:abstractText | A tryptic peptide of bovine beta-casein (amino acid residues 184-202) was used as a model antigen to investigate how the relative position of the (helper) T cell and B cell determinants on a protein antigen influences the antibody response. Immunization with the peptide elicited a considerably higher anti-peptide response in the C3H/He strain than in the C57BL/6 strain, despite the fact that the C57BL/6 T cells showed higher reactivity than the C3H/He T cells. The T cell and B cell determinants of the peptide were identified in these two strains. Each strain recognized a single B cell determinant and a single T cell determinant. In the C3H/He strain, the T and B cell determinants were located apart from one another, while the T and B cell determinants of the C57BL/6 strain were located in a region close each other. The results suggest that the level of an antibody response depends on the topological relationship of the T cell and B cell determinants on the antigen molecule. | lld:pubmed |
| pubmed-article:2141470 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2141470 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2141470 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2141470 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2141470 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2141470 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2141470 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2141470 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2141470 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:2141470 | pubmed:author | pubmed-author:EnomotoAA | lld:pubmed |
| pubmed-article:2141470 | pubmed:author | pubmed-author:KaminogawaSS | lld:pubmed |
| pubmed-article:2141470 | pubmed:author | pubmed-author:HachimuraSS | lld:pubmed |
| pubmed-article:2141470 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2141470 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:2141470 | pubmed:volume | 169 | lld:pubmed |
| pubmed-article:2141470 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2141470 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2141470 | pubmed:pagination | 803-8 | lld:pubmed |
| pubmed-article:2141470 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:meshHeading | pubmed-meshheading:2141470-... | lld:pubmed |
| pubmed-article:2141470 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2141470 | pubmed:articleTitle | Relative positioning of the T cell and B cell determinants on an immunogenic peptide: its influence on antibody response. | lld:pubmed |
| pubmed-article:2141470 | pubmed:affiliation | Department of Agricultural Chemistry, University of Tokyo, Japan. | lld:pubmed |
| pubmed-article:2141470 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2141470 | lld:pubmed |
