| pubmed-article:2140856 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2140856 | lifeskim:mentions | umls-concept:C1522564 | lld:lifeskim |
| pubmed-article:2140856 | lifeskim:mentions | umls-concept:C1337333 | lld:lifeskim |
| pubmed-article:2140856 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:2140856 | pubmed:dateCreated | 1990-7-12 | lld:pubmed |
| pubmed-article:2140856 | pubmed:abstractText | To determine whether technetium-99m-hexakis-2-methoxyisobutyl isonitrile (SESTAMIBI) remains fixed in the myocardium following its initial uptake or undergoes time-related redistribution, anesthetized dogs underwent occlusion of the anterior descending coronary artery for 6 min, followed by 3-hr reperfusion. Technetium-99m-SESTAMIBI and thallium-201 (201Tl) were injected intravenously after 1 min occlusion and regional myocardial blood flow was measured with radioactive microspheres. Tomographic imaging of Tc-SESTAMIBI revealed a perfusion defect with slight but definite filling in over 2 hr. Quantitative analysis indicated a significant rise in the nadir and decrease in the width of the defect in circumferential profile curves. After 3-hr of reperfusion, Tc-SESTAMIBI activity in the previously ischemic area was always greater than the activity of microspheres injected during coronary occlusion (mean normalized values, 0.32 versus 0.11, p less than 0.0001). Our results indicate that following transient ischemia and reperfusion, Tc-SESTAMIBI clearly undergoes myocardial redistribution, although more slowly and less completely than 201Tl. | lld:pubmed |
| pubmed-article:2140856 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2140856 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2140856 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2140856 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2140856 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2140856 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2140856 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2140856 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2140856 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:2140856 | pubmed:issn | 0161-5505 | lld:pubmed |
| pubmed-article:2140856 | pubmed:author | pubmed-author:WagnerH NHNJr | lld:pubmed |
| pubmed-article:2140856 | pubmed:author | pubmed-author:BeckerL CLC | lld:pubmed |
| pubmed-article:2140856 | pubmed:author | pubmed-author:LiQ SQS | lld:pubmed |
| pubmed-article:2140856 | pubmed:author | pubmed-author:FrankT LTL | lld:pubmed |
| pubmed-article:2140856 | pubmed:author | pubmed-author:SolowJJ | lld:pubmed |
| pubmed-article:2140856 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2140856 | pubmed:volume | 31 | lld:pubmed |
| pubmed-article:2140856 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2140856 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2140856 | pubmed:pagination | 1069-76 | lld:pubmed |
| pubmed-article:2140856 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:meshHeading | pubmed-meshheading:2140856-... | lld:pubmed |
| pubmed-article:2140856 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2140856 | pubmed:articleTitle | Myocardial redistribution of technetium-99m-methoxyisobutyl isonitrile (SESTAMIBI). | lld:pubmed |
| pubmed-article:2140856 | pubmed:affiliation | Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland. | lld:pubmed |
| pubmed-article:2140856 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2140856 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2140856 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2140856 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
