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pubmed-article:21377081pubmed:abstractTextThe dynamic physiologic response of human brain death and the impact of vasopressin on successful organ transplantation is reported. A 60-year-old woman was admitted to the intensive care unit after severe traumatic brain injury resulting in brain death. Initial Cushing reflex was followed by a precipitous decrease in systemic blood pressure that was refractory to the alpha-agonist phenylephrine. After intravenous vasopressin was given, hemodynamic stability was restored and maintained until successful organ transplantation. Vasopressin, a catecholamine-sparing vasopressor and antidiuretic agent, may be an effective agent in the treatment of refractory hypotension after brain death prior to organ transplantation.lld:pubmed
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pubmed-article:21377081pubmed:authorpubmed-author:TangJulin FJFlld:pubmed
pubmed-article:21377081pubmed:authorpubmed-author:NakagawaKazum...lld:pubmed
pubmed-article:21377081pubmed:copyrightInfoCopyright © 2011 Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:21377081pubmed:year2011lld:pubmed
pubmed-article:21377081pubmed:articleTitlePhysiologic response of human brain death and the use of vasopressin for successful organ transplantation.lld:pubmed
pubmed-article:21377081pubmed:affiliationNeurovascular Service, Department of Neurology, University of California, San Francisco, San Francisco General Hospital, San Francisco, CA 94110, USA.lld:pubmed
pubmed-article:21377081pubmed:publicationTypeJournal Articlelld:pubmed
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