Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating ?-tubulin Glu198 and prohibitin Asp40.

Source:http://linkedlifedata.com/resource/pubmed/id/21371445

Biochem. Pharmacol. 2011 May 1 81 9 1116-23

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21371445