C-terminal-truncated apolipoprotein (apo) E4 inefficiently clears amyloid-beta (Abeta) and acts in concert with Abeta to elicit neuronal and behavioral deficits in mice.

Source:http://linkedlifedata.com/resource/pubmed/id/21368138

Proc. Natl. Acad. Sci. U.S.A. 2011 Mar 8 108 10 4236-41

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PMID
21368138