| pubmed-article:21338051 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C1446409 | lld:lifeskim |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C0268563 | lld:lifeskim |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C1709060 | lld:lifeskim |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:21338051 | lifeskim:mentions | umls-concept:C2348042 | lld:lifeskim |
| pubmed-article:21338051 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:21338051 | pubmed:dateCreated | 2011-3-14 | lld:pubmed |
| pubmed-article:21338051 | pubmed:abstractText | Using a functional high-throughput screening (HTS) and subsequent solution-phase parallel synthesis approach, we have discovered a novel series of positive allosteric modulators for mGlu?, a G-protein coupled receptor. This series is comprised of a homopiperazine central core. The solution-phase parallel synthesis and SAR of analogs derived from this series will be presented. This series of positive allosteric modulators of mGlu? provide critical research tools to further probe the mGlu?-mediated effects in Parkinson's disease. | lld:pubmed |
| pubmed-article:21338051 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21338051 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21338051 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21338051 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21338051 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21338051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21338051 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21338051 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21338051 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:21338051 | pubmed:issn | 2156-8944 | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:NiswenderColl... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:BlobaumAnna... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:ConnP... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:LindsleyCraig... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:CheungYiu-Yin... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:WeaverC... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:HopkinsCorey... | lld:pubmed |
| pubmed-article:21338051 | pubmed:author | pubmed-author:ZamoranoRocio... | lld:pubmed |
| pubmed-article:21338051 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21338051 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:21338051 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:21338051 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21338051 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21338051 | pubmed:pagination | 159-65 | lld:pubmed |
| pubmed-article:21338051 | pubmed:dateRevised | 2011-9-13 | lld:pubmed |
| pubmed-article:21338051 | pubmed:meshHeading | pubmed-meshheading:21338051... | lld:pubmed |
| pubmed-article:21338051 | pubmed:meshHeading | pubmed-meshheading:21338051... | lld:pubmed |
| pubmed-article:21338051 | pubmed:meshHeading | pubmed-meshheading:21338051... | lld:pubmed |
| pubmed-article:21338051 | pubmed:meshHeading | pubmed-meshheading:21338051... | lld:pubmed |
| pubmed-article:21338051 | pubmed:meshHeading | pubmed-meshheading:21338051... | lld:pubmed |
| pubmed-article:21338051 | pubmed:meshHeading | pubmed-meshheading:21338051... | lld:pubmed |
| pubmed-article:21338051 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21338051 | pubmed:articleTitle | Solution-phase parallel synthesis and SAR of homopiperazinyl analogs as positive allosteric modulators of mGlu?. | lld:pubmed |
| pubmed-article:21338051 | pubmed:affiliation | Department of Pharmacology, Vanderbilt Program in Drug Discovery, Vanderbilt University Medical Center, Nashville, TN 37232, United States. | lld:pubmed |
| pubmed-article:21338051 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21338051 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:21338051 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
