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pubmed-article:21334779pubmed:abstractTextAcute otitis media is the most common respiratory tract infection in infancy and early childhood that is managed with antimicrobial agents. Ninety-three per cent of the cases diagnosed in Spain are treated with antibiotics, and Streptococcus pneumoniae and untypeable Haemophilus influenzae are the most frequently isolated pathogens. The aim of this work was to evaluate the usefulness of amoxicillin, amoxicillin/clavulanate and ceftriaxone for the empirical treatment of acute otitis media, looking at the pharmacokinetic variability and the antimicrobial susceptibility of paediatric strains of the two main pathogens responsible for AOM in Spain, Streptococcus pneumoniae and Haemophilus influenzae.lld:pubmed
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pubmed-article:21334779pubmed:authorpubmed-author:PedrazJosé...lld:pubmed
pubmed-article:21334779pubmed:authorpubmed-author:GascónAlicia...lld:pubmed
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pubmed-article:21334779pubmed:authorpubmed-author:Martín-Herrer...lld:pubmed
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pubmed-article:21334779pubmed:copyrightInfoCopyright © 2009 Elsevier España, S.L. All rights reserved.lld:pubmed
pubmed-article:21334779pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21334779pubmed:volume29lld:pubmed
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pubmed-article:21334779pubmed:pagination167-73lld:pubmed
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pubmed-article:21334779pubmed:year2011lld:pubmed
pubmed-article:21334779pubmed:articleTitlePharmacokinetic/pharmacodynamic evaluation of amoxicillin, amoxicillin/clavulanate and ceftriaxone in the treatment of paediatric acute otitis media in Spain.lld:pubmed
pubmed-article:21334779pubmed:affiliationPharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of the Basque Country, Vitoria, Spain.lld:pubmed
pubmed-article:21334779pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21334779pubmed:publicationTypeComparative Studylld:pubmed
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