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pubmed-article:21321929pubmed:abstractTextWe have previously demonstrated that in response to transforming growth factor ? (TGF?), Fli-1 activity is repressed through a series of sequential posttranslational modifications, consisting of protein kinase C? (PKC?)-induced Thr312 phosphorylation, acetylation by p300/CREB binding protein-associated factor, and detachment from the collagen promoter. The purpose of this study was to further investigate the upstream events that lead to Fli-1 phosphorylation in response to TGF?.lld:pubmed
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pubmed-article:21321929pubmed:articleTitleThe c-Abl tyrosine kinase controls protein kinase C?-induced Fli-1 phosphorylation in human dermal fibroblasts.lld:pubmed
pubmed-article:21321929pubmed:affiliationBoston University School of Medicine, Arthritis Center-Rheumatology, Boston, Massachusetts 02118, USA.lld:pubmed
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