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pubmed-article:21317651pubmed:abstractTextStatins may be important for the prevention and management of sepsis; however, through their impact on ubiquinone synthesis, they may impair mitochondrial and organ function in the septic patient. Here we provide a narrative review of the function and roles of ubiquinone in cellular metabolism, the interactions with statins, and the potential consequences in the critically ill.lld:pubmed
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pubmed-article:21317651pubmed:authorpubmed-author:SingerMervynMlld:pubmed
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pubmed-article:21317651pubmed:year2011lld:pubmed
pubmed-article:21317651pubmed:articleTitlePotential metabolic consequences of statins in sepsis.lld:pubmed
pubmed-article:21317651pubmed:affiliationUniversity College Hospitals NHS Foundation Trust, University College London, London, United Kingdom.lld:pubmed
pubmed-article:21317651pubmed:publicationTypeJournal Articlelld:pubmed
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