pubmed-article:21262866 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C0011860 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C1140621 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C1801960 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C1521970 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:21262866 | lifeskim:mentions | umls-concept:C0587107 | lld:lifeskim |
pubmed-article:21262866 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:21262866 | pubmed:dateCreated | 2011-1-25 | lld:pubmed |
pubmed-article:21262866 | pubmed:abstractText | In this study we tested the hypothesis that type 2 diabetes impairs the dynamic response of leg vascular conductance (LVC) during exercise. LVC (leg blood flow/mean arterial pressure) responses were studied during intermittent contractions of the calf muscle in subjects with type 2 diabetes (n = 9), heavy controls (n = 10) and lean controls (n = 8) using a biexponential function and an estimate of the mean response time (MRT). The time constant of the second phase of LVC was significantly greater in type 2 diabetes (66.4 ± 29.2 s) than the heavy (22.2 ± 13.4 s) and lean (21.8 ± 9.3 s) controls, resulting in a significantly greater MRT in the diabetic group (median [IQR] = 30.7 [24.6-46.5] s versus 16.3 [4.3-23.2] s and 18.4 [13.7-19.3] s). These data support the hypothesis and suggest that a slowed hyperaemic response in the exercising limb might contribute to exercise intolerance in diabetic subjects. | lld:pubmed |
pubmed-article:21262866 | pubmed:language | eng | lld:pubmed |
pubmed-article:21262866 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21262866 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:21262866 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:21262866 | pubmed:month | Jan | lld:pubmed |
pubmed-article:21262866 | pubmed:issn | 1752-8984 | lld:pubmed |
pubmed-article:21262866 | pubmed:author | pubmed-author:GreenSimonS | lld:pubmed |
pubmed-article:21262866 | pubmed:author | pubmed-author:O'SheaDonalD | lld:pubmed |
pubmed-article:21262866 | pubmed:author | pubmed-author:EgañaMikelM | lld:pubmed |
pubmed-article:21262866 | pubmed:author | pubmed-author:ReillyHeather... | lld:pubmed |
pubmed-article:21262866 | pubmed:author | pubmed-author:MacAnaneyOsca... | lld:pubmed |
pubmed-article:21262866 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:21262866 | pubmed:volume | 8 | lld:pubmed |
pubmed-article:21262866 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:21262866 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:21262866 | pubmed:pagination | 12-21 | lld:pubmed |
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pubmed-article:21262866 | pubmed:year | 2011 | lld:pubmed |
pubmed-article:21262866 | pubmed:articleTitle | Effect of type 2 diabetes on the dynamic response characteristics of leg vascular conductance during exercise. | lld:pubmed |
pubmed-article:21262866 | pubmed:affiliation | Department of Physiology, Trinity College Dublin, Dublin, Ireland. | lld:pubmed |
pubmed-article:21262866 | pubmed:publicationType | Journal Article | lld:pubmed |