| pubmed-article:21262571 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0038477 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0439611 | lld:lifeskim |
| pubmed-article:21262571 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:21262571 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:21262571 | pubmed:dateCreated | 2011-2-7 | lld:pubmed |
| pubmed-article:21262571 | pubmed:abstractText | A series of novel benzothiazole-2-thiol derivatives were synthesized, and their anti-proliferative activities on HepG2 and MCF-7 cells were investigated. Most compounds had inhibitory effects on cell growth, and some of them were more effective than cisplatin. Compounds 6m and 6t displayed good inhibitory activities against a panel of different types of human cancer cell lines, with IC(50) values in the low micromolar range. Further biological evaluation indicated that 6m induced apoptosis in HepG2 cancer cells. Structure-activity relationships were also proposed. | lld:pubmed |
| pubmed-article:21262571 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21262571 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21262571 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21262571 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21262571 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21262571 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21262571 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21262571 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21262571 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:21262571 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:WilkE KEK | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:YangLiL | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:HuangTing-Tin... | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:WangZhaoZ | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:WeiYu-QuanYQ | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:LiYan-FangYF | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:ZhouTianT | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:ZhaoYing-LanY... | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:YuLuo-TingLT | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:YangSheng-Yon... | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:ShiXuan-HongX... | lld:pubmed |
| pubmed-article:21262571 | pubmed:author | pubmed-author:XuYou-ZhiYZ | lld:pubmed |
| pubmed-article:21262571 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Ltd. All rights reserved. | lld:pubmed |
| pubmed-article:21262571 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21262571 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:21262571 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:21262571 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21262571 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21262571 | pubmed:pagination | 1097-101 | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:meshHeading | pubmed-meshheading:21262571... | lld:pubmed |
| pubmed-article:21262571 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21262571 | pubmed:articleTitle | Synthesis, structure-activity relationships and preliminary antitumor evaluation of benzothiazole-2-thiol derivatives as novel apoptosis inducers. | lld:pubmed |
| pubmed-article:21262571 | pubmed:affiliation | State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Sichuan 610041, China. | lld:pubmed |
| pubmed-article:21262571 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21262571 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:21262571 | lld:chembl |
