Linked Life Data

21259367

Source:http://linkedlifedata.com/resource/pubmed/id/21259367

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:21259367rdf:typepubmed:Citationlld:pubmed
pubmed-article:21259367lifeskim:mentionsumls-concept:C0086418lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C0005767lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C0042817lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C0282636lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C1710082lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C0439810lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C0392747lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C1655730lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C1705491lld:lifeskim
pubmed-article:21259367lifeskim:mentionsumls-concept:C0338207lld:lifeskim
pubmed-article:21259367pubmed:issue1lld:pubmed
pubmed-article:21259367pubmed:dateCreated2011-1-24lld:pubmed
pubmed-article:21259367pubmed:abstractTextThe characterisation of the extravascular (EV) contribution to the blood oxygenation level-dependent (BOLD) effect is important for understanding the spatial specificity of BOLD contrast and for modelling approaches that aim to extract quantitative metabolic parameters from the BOLD signal. Using bipolar crusher gradients, total (b?=?0?s/mm(2) ) and predominantly EV (b?=?100?s/mm(2) ) gradient echo BOLD ?R(2)* and signal changes (?S/S) in response to visual stimulation (flashing checkerboard; f?=?8?Hz) were investigated sequentially (within?<?3?h) at 1.5, 3.0 and 7.0 T in the same subgroup of healthy volunteers (n?=?7) and at identical spatial resolutions (3.5?×?3.5?×?3.5?mm(3)). Total ?R(2)* (z-score analysis) values were -0.61?±?0.10?s(-1) (1.5 T), -0.74?±?0.05?s(-1) (3.0 T) and -1.37?±?0.12?s(-1) (7.0 T), whereas EV ?R(2)* values were -0.28?±?0.07?s(-1) (1.5 T), -0.52?±?0.07?s(-1) (3.0 T) and -1.25?±?0.11?s(-1) (7.0 T). Although EV ?R(2)* increased linearly with field, as expected, it was found that EV ?S/S increased less than linearly with field in a manner that varied with TE choice. Furthermore, unlike ?R(2)*, total and EV ?S/S did not converge at 7.0 T. These trends were similar whether a z-score analysis or occipital lobe-based region-of-interest approach was used for voxel selection. These findings suggest that calibrated BOLD approaches may benefit from an EV ?R(2)* measurement as opposed to a ?S/S measurement at a single TE.lld:pubmed
pubmed-article:21259367pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21259367pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21259367pubmed:languageenglld:pubmed
pubmed-article:21259367pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21259367pubmed:citationSubsetIMlld:pubmed
pubmed-article:21259367pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:21259367pubmed:statusMEDLINElld:pubmed
pubmed-article:21259367pubmed:monthJanlld:pubmed
pubmed-article:21259367pubmed:issn1099-1492lld:pubmed
pubmed-article:21259367pubmed:authorpubmed-author:JezzardPeterPlld:pubmed
pubmed-article:21259367pubmed:authorpubmed-author:van...lld:pubmed
pubmed-article:21259367pubmed:authorpubmed-author:HendrikseJero...lld:pubmed
pubmed-article:21259367pubmed:authorpubmed-author:HoogduinHansHlld:pubmed
pubmed-article:21259367pubmed:authorpubmed-author:DonahueManus...lld:pubmed
pubmed-article:21259367pubmed:authorpubmed-author:LuijtenPeter...lld:pubmed
pubmed-article:21259367pubmed:copyrightInfoCopyright © 2010 John Wiley & Sons, Ltd.lld:pubmed
pubmed-article:21259367pubmed:issnTypeElectroniclld:pubmed
pubmed-article:21259367pubmed:volume24lld:pubmed
pubmed-article:21259367pubmed:ownerNLMlld:pubmed
pubmed-article:21259367pubmed:authorsCompleteYlld:pubmed
pubmed-article:21259367pubmed:pagination25-34lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:meshHeadingpubmed-meshheading:21259367...lld:pubmed
pubmed-article:21259367pubmed:year2011lld:pubmed
pubmed-article:21259367pubmed:articleTitleBlood oxygenation level-dependent (BOLD) total and extravascular signal changes and ?R2* in human visual cortex at 1.5, 3.0 and 7.0 T.lld:pubmed
pubmed-article:21259367pubmed:affiliationFMRIB Centre, Department of Clinical Neurology, University of Oxford, Oxford, UK. mjd@jhu.edulld:pubmed
pubmed-article:21259367pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:21259367pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:21259367pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed