pubmed-article:21251280 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C0018787 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C0010531 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C0061355 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C1704259 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C1705987 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C0521116 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
pubmed-article:21251280 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
pubmed-article:21251280 | pubmed:dateCreated | 2011-2-11 | lld:pubmed |
pubmed-article:21251280 | pubmed:abstractText | Glucagon-like peptide-1 (GLP-1) is a hormone predominately synthesized and secreted by intestinal L-cells. GLP-1 modulates multiple cellular functions and its receptor agonists are now used clinically for diabetic treatment. Interestingly, preclinical and clinical evidence suggests that GLP-1 agonists produce beneficial effects on dysfunctional hearts via acting on myocardial GLP-1 receptors. As the effects of GLP-1 on myocyte electrophysiology are largely unknown, this study was to assess if GLP-1 could affect the cardiac voltage-gated L-type Ca2+ current (I(Ca)). | lld:pubmed |
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pubmed-article:21251280 | pubmed:language | eng | lld:pubmed |
pubmed-article:21251280 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:21251280 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:21251280 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:21251280 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:21251280 | pubmed:issn | 1475-2840 | lld:pubmed |
pubmed-article:21251280 | pubmed:author | pubmed-author:XiaoYong-FuYF | lld:pubmed |
pubmed-article:21251280 | pubmed:author | pubmed-author:SiggDaniel... | lld:pubmed |
pubmed-article:21251280 | pubmed:author | pubmed-author:NikolskayaAle... | lld:pubmed |
pubmed-article:21251280 | pubmed:author | pubmed-author:JayeDeborah... | lld:pubmed |
pubmed-article:21251280 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:21251280 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:21251280 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:21251280 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:21251280 | pubmed:pagination | 6 | lld:pubmed |
pubmed-article:21251280 | pubmed:dateRevised | 2011-7-25 | lld:pubmed |
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pubmed-article:21251280 | pubmed:year | 2011 | lld:pubmed |
pubmed-article:21251280 | pubmed:articleTitle | Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway. | lld:pubmed |
pubmed-article:21251280 | pubmed:affiliation | Cardiac Rhythm Disease Management, Medtronic, Inc., 8200 Coral Sea Street NE, Mounds View, MN 55112, USA. yong-fu.xiao@medtronic.com | lld:pubmed |