| pubmed-article:21230516 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C0233494 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C0750572 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C0032521 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C0441722 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:21230516 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:21230516 | pubmed:issue | 5 Pt 1 | lld:pubmed |
| pubmed-article:21230516 | pubmed:dateCreated | 2011-1-14 | lld:pubmed |
| pubmed-article:21230516 | pubmed:abstractText | With the aid of brownian dynamics models, it is possible to estimate polymer tension by monitoring polymers' transverse thermal fluctuations. To assess the precision of the approach, brownian dynamics-based tension estimates were compared with the force applied to rhodamine-phalloidin labeled actin filaments bound to polymer beads and suspended between two optical traps. The transverse thermal fluctuations of each filament were monitored with a CCD camera, and the images were analyzed to obtain the filament's transverse displacement variance as a function of position along the filament, the filament's tension, and the camera's exposure time. A linear Brownian dynamics model was used to estimate the filament's tension. The estimated force was compared and agreed within 30% (when the tension <0.1 pN ) and 70% (when the tension <1 pN ) with the applied trap force. In addition, the paper presents concise asymptotic expressions for the mechanical compliance of a system consisting of a filament attached tangentially to bead handles (dumbbell system). The techniques described here can be used for noncontact estimates of polymers' and fibers' tension. | lld:pubmed |
| pubmed-article:21230516 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21230516 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21230516 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21230516 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21230516 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21230516 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21230516 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:21230516 | pubmed:issn | 1550-2376 | lld:pubmed |
| pubmed-article:21230516 | pubmed:author | pubmed-author:ShumanHenryH | lld:pubmed |
| pubmed-article:21230516 | pubmed:author | pubmed-author:GoldmanYale... | lld:pubmed |
| pubmed-article:21230516 | pubmed:author | pubmed-author:BauHaim HHH | lld:pubmed |
| pubmed-article:21230516 | pubmed:author | pubmed-author:PurohitPrasha... | lld:pubmed |
| pubmed-article:21230516 | pubmed:author | pubmed-author:ArsenaultMark... | lld:pubmed |
| pubmed-article:21230516 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21230516 | pubmed:volume | 82 | lld:pubmed |
| pubmed-article:21230516 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21230516 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21230516 | pubmed:pagination | 051923 | lld:pubmed |
| pubmed-article:21230516 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:meshHeading | pubmed-meshheading:21230516... | lld:pubmed |
| pubmed-article:21230516 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:21230516 | pubmed:articleTitle | Comparison of Brownian-dynamics-based estimates of polymer tension with direct force measurements. | lld:pubmed |
| pubmed-article:21230516 | pubmed:affiliation | Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Towne Building, 220 S. 33rd St., Philadelphia, Pennsylvania 19104-6315, USA. | lld:pubmed |
| pubmed-article:21230516 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21230516 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:21230516 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:21230516 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
