| pubmed-article:21214959 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21214959 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
| pubmed-article:21214959 | lifeskim:mentions | umls-concept:C1257806 | lld:lifeskim |
| pubmed-article:21214959 | lifeskim:mentions | umls-concept:C0172973 | lld:lifeskim |
| pubmed-article:21214959 | lifeskim:mentions | umls-concept:C1417671 | lld:lifeskim |
| pubmed-article:21214959 | lifeskim:mentions | umls-concept:C0181586 | lld:lifeskim |
| pubmed-article:21214959 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21214959 | pubmed:dateCreated | 2011-1-25 | lld:pubmed |
| pubmed-article:21214959 | pubmed:abstractText | NEK1, the first mammalian ortholog of the fungal protein kinase never-in-mitosis A (NIMA), is involved early in the DNA damage sensing/repair pathway. A defect in DNA repair in NEK1-deficient cells is suggested by persistence of DNA double strand breaks after low dose ionizing radiation (IR). NEK1-deficient cells also fail to activate the checkpoint kinases CHK1 and CHK2, and fail to arrest properly at G1/S or G2/M-phase checkpoints after DNA damage. | lld:pubmed |
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| pubmed-article:21214959 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21214959 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21214959 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:21214959 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21214959 | pubmed:issn | 1476-4598 | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:PolciRosariaR | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:EdwardsRobert... | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:ChenPhang-Lan... | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:ChenChi-FenCF | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:RileyDaniel... | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:ChenYumayY | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:HanselDonna... | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:ChiangHuai-Ch... | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:PenaMichelleM | lld:pubmed |
| pubmed-article:21214959 | pubmed:author | pubmed-author:WeiRandy LRL | lld:pubmed |
| pubmed-article:21214959 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21214959 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:21214959 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21214959 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21214959 | pubmed:pagination | 5 | lld:pubmed |
| pubmed-article:21214959 | pubmed:dateRevised | 2011-7-20 | lld:pubmed |
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| pubmed-article:21214959 | pubmed:meshHeading | pubmed-meshheading:21214959... | lld:pubmed |
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| pubmed-article:21214959 | pubmed:meshHeading | pubmed-meshheading:21214959... | lld:pubmed |
| pubmed-article:21214959 | pubmed:meshHeading | pubmed-meshheading:21214959... | lld:pubmed |
| pubmed-article:21214959 | pubmed:meshHeading | pubmed-meshheading:21214959... | lld:pubmed |
| pubmed-article:21214959 | pubmed:meshHeading | pubmed-meshheading:21214959... | lld:pubmed |
| pubmed-article:21214959 | pubmed:meshHeading | pubmed-meshheading:21214959... | lld:pubmed |
| pubmed-article:21214959 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21214959 | pubmed:articleTitle | Mutation of NIMA-related kinase 1 (NEK1) leads to chromosome instability. | lld:pubmed |
| pubmed-article:21214959 | pubmed:affiliation | Department of Medicine, Division of Endocrinology, University of California at Irvine, 1130 Gross Hall, Irvine, CA 92697, USA. yumayc@uci.edu | lld:pubmed |
| pubmed-article:21214959 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21214959 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:21214959 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:21214959 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:18004 | entrezgene:pubmed | pubmed-article:21214959 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21214959 | lld:entrezgene |
