Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.

Source:http://linkedlifedata.com/resource/pubmed/id/21175203

J. Am. Chem. Soc. 2011 Feb 2 133 4 976-85

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21175203