| pubmed-article:2117332 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C0012472 | lld:lifeskim |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C0032979 | lld:lifeskim |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C0033568 | lld:lifeskim |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C0085191 | lld:lifeskim |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C0178602 | lld:lifeskim |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2117332 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:2117332 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2117332 | pubmed:dateCreated | 1990-9-14 | lld:pubmed |
| pubmed-article:2117332 | pubmed:abstractText | Milligram-range doses of E2 prostaglandins have long been used to induce labor or abortion in the second and third trimesters of pregnancy. Enprostil, a synthetic dehydroprostaglandin E2 structural analogue, is administered in microgram doses for the treatment of acute duodenal ulcer and acute gastric ulcer. This study examined the effect of the ulcer-healing dose and twice the ulcer-healing dose upon women in the first trimester of pregnancy. Two hundred and seven women who had requested legal abortion in the first trimester participated in two randomized, double-blind, placebo-controlled, parallel studies. They received two doses of enprostil 35 micrograms (the recommended dose for the treatment of duodenal and gastric ulcer) (n = 51), 70 micrograms (twice the recommended dose) (n = 53), or placebo (n = 103) 12 h apart. No drug-induced abortions occurred in any of the first-trimester pregnancies. Vaginal bleeding occurred in 4% of volunteers receiving the lower dose and 4% receiving the higher dose of enprostil. Vaginal bleeding occurred in up to 2% of volunteers on placebo. Although not recommended for pregnant women, if enprostil is given inadvertently to pregnant women with ulcers, it is unlikely to endanger the pregnancy during the first trimester. | lld:pubmed |
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| pubmed-article:2117332 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2117332 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2117332 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2117332 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2117332 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2117332 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2117332 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2117332 | pubmed:issn | 0001-6349 | lld:pubmed |
| pubmed-article:2117332 | pubmed:author | pubmed-author:BergquistCC | lld:pubmed |
| pubmed-article:2117332 | pubmed:author | pubmed-author:JacobsonJJ | lld:pubmed |
| pubmed-article:2117332 | pubmed:author | pubmed-author:HuovinenKK | lld:pubmed |
| pubmed-article:2117332 | pubmed:author | pubmed-author:RydnertJJ | lld:pubmed |
| pubmed-article:2117332 | pubmed:author | pubmed-author:BokströmHH | lld:pubmed |
| pubmed-article:2117332 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2117332 | pubmed:volume | 69 | lld:pubmed |
| pubmed-article:2117332 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2117332 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2117332 | pubmed:pagination | 135-8 | lld:pubmed |
| pubmed-article:2117332 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
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| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:meshHeading | pubmed-meshheading:2117332-... | lld:pubmed |
| pubmed-article:2117332 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2117332 | pubmed:articleTitle | No abortion-inducing effect of the ulcer-healing dose of the synthetic prostaglandin E2 analogue enprostil in first trimester. | lld:pubmed |
| pubmed-article:2117332 | pubmed:affiliation | Department of Obstetrics and Gynecology of Södertälji Skukhus, Sweden. | lld:pubmed |
| pubmed-article:2117332 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2117332 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2117332 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2117332 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:2117332 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
