| pubmed-article:21173231 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C0036658 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C0007012 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C0018358 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:21173231 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:21173231 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21173231 | pubmed:dateCreated | 2011-1-5 | lld:pubmed |
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| pubmed-article:21173231 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21173231 | pubmed:abstractText | CO(2) is both a critical regulator of animal physiology and an important sensory cue for many animals for host detection, food location, and mate finding. The free-living soil nematode Caenorhabditis elegans shows CO(2) avoidance behavior, which requires a pair of ciliated sensory neurons, the BAG neurons. Using in vivo calcium imaging, we show that CO(2) specifically activates the BAG neurons and that the CO(2)-sensing function of BAG neurons requires TAX-2/TAX-4 cyclic nucleotide-gated ion channels and the receptor-type guanylate cyclase GCY-9. Our results delineate a molecular pathway for CO(2) sensing and suggest that activation of a receptor-type guanylate cyclase is an evolutionarily conserved mechanism by which animals detect environmental CO(2). | lld:pubmed |
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| pubmed-article:21173231 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:21173231 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:21173231 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21173231 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:21173231 | pubmed:issn | 1091-6490 | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:SternbergPaul... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:MillerDavid... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:HorvitzH... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:RätschGunnarG | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:HallemElissa... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:HenzStefan... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:RingstadNiels... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:SpencerW... | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:ZellerGeorgG | lld:pubmed |
| pubmed-article:21173231 | pubmed:author | pubmed-author:McWhirterRebe... | lld:pubmed |
| pubmed-article:21173231 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21173231 | pubmed:day | 4 | lld:pubmed |
| pubmed-article:21173231 | pubmed:volume | 108 | lld:pubmed |
| pubmed-article:21173231 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21173231 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21173231 | pubmed:pagination | 254-9 | lld:pubmed |
| pubmed-article:21173231 | pubmed:dateRevised | 2011-8-1 | lld:pubmed |
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