| pubmed-article:21152875 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21152875 | lifeskim:mentions | umls-concept:C0021344 | lld:lifeskim |
| pubmed-article:21152875 | lifeskim:mentions | umls-concept:C0035647 | lld:lifeskim |
| pubmed-article:21152875 | lifeskim:mentions | umls-concept:C0005684 | lld:lifeskim |
| pubmed-article:21152875 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:21152875 | lifeskim:mentions | umls-concept:C0205281 | lld:lifeskim |
| pubmed-article:21152875 | lifeskim:mentions | umls-concept:C0031928 | lld:lifeskim |
| pubmed-article:21152875 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:21152875 | pubmed:dateCreated | 2010-12-24 | lld:pubmed |
| pubmed-article:21152875 | pubmed:abstractText | The relationship between urothelial bladder cancer and high-risk human papillomaviruses (HR-HPV) is still a poorly understood entity, even if some studies have supposed a probably correlation. The aim of the present study was to assess the potential relationship between the presence of HR-HPV and non-muscle invasive urothelial bladder cancers (NMIBC). One hundred and thirty-seven subjects (78 patients affected by NMIBC and 59 controls) were recruited in this prospective study. HR-HPV DNA was evaluated both in urine and tumour tissues. Data from patients were compared with data from controls. The relationship between patients and controls, in terms of HR-HPV presence was performed. The relationship between all pathological data and HR-HPV presence in patient group was carried out. HR-HPV DNA in tissue was found in 27 of 78 (34.6%) tumour samples and in 6 of 59 (10.1%) specimens from TUR-P, with a statistically significant difference (p=0.0009; dF=1; ?2=10.98). HR-HPV DNA in urine was found in 36 of 78 (46.1%) samples obtained from patients, whereas in only 8 of 59 (13.5%) samples from controls (p<0.0001: dF=1; ?2=16.37). A statistical significant difference in terms of HR-HPV frequency between high-grade and low-grade urothelial bladder cancer, was found (p=0.032; RR=0.52-95% CI 0.27-0.93; OR=0.34-95% CI 0.13-0.90). In conclusion, this study highlights the correlation between urothelial bladder cancer and high-risk type HPV infection, suggesting the potential etiopathogenetic role of HR-HPV in urothelial bladder cancer development. | lld:pubmed |
| pubmed-article:21152875 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21152875 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21152875 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21152875 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21152875 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21152875 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:21152875 | pubmed:issn | 1791-2431 | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:GeppettiPiera... | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:BartolettiRic... | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:NesiGabriella... | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:MalossiniGian... | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:MeacciFrances... | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:CaiTommasoT | lld:pubmed |
| pubmed-article:21152875 | pubmed:author | pubmed-author:MazzoliSandra... | lld:pubmed |
| pubmed-article:21152875 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21152875 | pubmed:volume | 25 | lld:pubmed |
| pubmed-article:21152875 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21152875 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21152875 | pubmed:pagination | 485-9 | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
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| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:meshHeading | pubmed-meshheading:21152875... | lld:pubmed |
| pubmed-article:21152875 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21152875 | pubmed:articleTitle | Human papillomavirus and non-muscle invasive urothelial bladder cancer: potential relationship from a pilot study. | lld:pubmed |
| pubmed-article:21152875 | pubmed:affiliation | Department of Urology, Santa Chiara Hospital, Largo Medaglie d'Oro 9, Trento, Italy. ktommy@libero.it | lld:pubmed |
| pubmed-article:21152875 | pubmed:publicationType | Journal Article | lld:pubmed |
