| pubmed-article:21142106 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21142106 | lifeskim:mentions | umls-concept:C0023237 | lld:lifeskim |
| pubmed-article:21142106 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:21142106 | lifeskim:mentions | umls-concept:C1417170 | lld:lifeskim |
| pubmed-article:21142106 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:21142106 | lifeskim:mentions | umls-concept:C0031951 | lld:lifeskim |
| pubmed-article:21142106 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:21142106 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21142106 | pubmed:dateCreated | 2011-9-15 | lld:pubmed |
| pubmed-article:21142106 | pubmed:abstractText | The macrophage infectivity potentiator (MIP) protein is a major virulence factor of Legionella pneumophila, the causative agent of Legionnaires' disease. MIP belongs to the FK506-binding proteins (FKBP) and is necessary for optimal intracellular survival and lung tissue dissemination of L. pneumophila. We aimed to identify new small-molecule inhibitors of MIP by starting from known FKBP12 ligands. Computational analysis, synthesis, and biological testing of pipecolic acid derivatives revealed a promising scaffold for new MIP inhibitors. | lld:pubmed |
| pubmed-article:21142106 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21142106 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21142106 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21142106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21142106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21142106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21142106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21142106 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21142106 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21142106 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:21142106 | pubmed:issn | 1520-4804 | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:SteinertMicha... | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:HolzgrabeUlri... | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:SchweimerKris... | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:SotrifferChri... | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:SippelMartinM | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:RöschPaulP | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:WeiwadMatthia... | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:ThieleAlexand... | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:JägerJensJ | lld:pubmed |
| pubmed-article:21142106 | pubmed:author | pubmed-author:JuliChristina... | lld:pubmed |
| pubmed-article:21142106 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21142106 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:21142106 | pubmed:volume | 54 | lld:pubmed |
| pubmed-article:21142106 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21142106 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21142106 | pubmed:pagination | 277-83 | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:meshHeading | pubmed-meshheading:21142106... | lld:pubmed |
| pubmed-article:21142106 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21142106 | pubmed:articleTitle | Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein. | lld:pubmed |
| pubmed-article:21142106 | pubmed:affiliation | Institute of Pharmacy and Food Chemistry, University of Wu?rzburg, Wu?rzburg, Germany. | lld:pubmed |
| pubmed-article:21142106 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21142106 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:21142106 | lld:chembl |
