| pubmed-article:21136242 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21136242 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:21136242 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
| pubmed-article:21136242 | lifeskim:mentions | umls-concept:C2709248 | lld:lifeskim |
| pubmed-article:21136242 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:21136242 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:21136242 | pubmed:dateCreated | 2010-12-7 | lld:pubmed |
| pubmed-article:21136242 | pubmed:abstractText | CASE REPORT: In a 45 year old patient pulmonary, renal and ocular manifestations of ANCA-associated vasculitis is reported that required immunosuppressive therapy. On admission the patient complained about enduring lower abdominal pain. A CT scan revealed free intraabdominal fluid and dilated small intestine filled with fluid. Laparotomy was performed with the working diagnosis of paralytic ileus. Intraoperatively, hemorrhagic-necrotic alterations of the small intestinal wall were conspicuous and resected. Microscopic examination revealed transmural ischemic necrosis of the resected intestinal tissue with prominent granulomatous vasculitis of arteries. CD20-antibody rituximab was applied due to the life-threatening condition and as ultima ratio therapy. Subsequently the disease activity was controlled, renal function improved and abdominal discomfort subsided. CONCLUSION: Gastrointestinal involvement with necrotizing vasculitis is an uncommon but serious complication. Most patients respond to established therapy protocols encompassing cyclophosphamide and glucocorticoids. Administration of rituximab may be a promising alternative in refractory cases. | lld:pubmed |
| pubmed-article:21136242 | pubmed:language | ger | lld:pubmed |
| pubmed-article:21136242 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21136242 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21136242 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21136242 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21136242 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21136242 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21136242 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:21136242 | pubmed:issn | 1615-6722 | lld:pubmed |
| pubmed-article:21136242 | pubmed:author | pubmed-author:MertensPeter... | lld:pubmed |
| pubmed-article:21136242 | pubmed:author | pubmed-author:SteinbachJörg... | lld:pubmed |
| pubmed-article:21136242 | pubmed:author | pubmed-author:NeumannKlaus... | lld:pubmed |
| pubmed-article:21136242 | pubmed:author | pubmed-author:BartschPeterP | lld:pubmed |
| pubmed-article:21136242 | pubmed:author | pubmed-author:BosselmannHan... | lld:pubmed |
| pubmed-article:21136242 | pubmed:author | pubmed-author:LangerDorothe... | lld:pubmed |
| pubmed-article:21136242 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21136242 | pubmed:volume | 105 | lld:pubmed |
| pubmed-article:21136242 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21136242 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21136242 | pubmed:pagination | 831-6 | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:meshHeading | pubmed-meshheading:21136242... | lld:pubmed |
| pubmed-article:21136242 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:21136242 | pubmed:articleTitle | [Necrotizing granulomatosis with pulmonary, intestinal and renal involvement]. | lld:pubmed |
| pubmed-article:21136242 | pubmed:affiliation | Universitätsklinik für Nieren- und Hochdruckkrankheiten & Bereich Endokrinologie und Stoffwechselkrankheiten, Universitätsklinikum Magdeburg, Magdeburg, Germany. joerg.steinbach@med.ovgu.de | lld:pubmed |
| pubmed-article:21136242 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21136242 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:21136242 | pubmed:publicationType | Case Reports | lld:pubmed |
