| pubmed-article:21129964 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21129964 | lifeskim:mentions | umls-concept:C0034809 | lld:lifeskim |
| pubmed-article:21129964 | lifeskim:mentions | umls-concept:C0231491 | lld:lifeskim |
| pubmed-article:21129964 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:21129964 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21129964 | pubmed:dateCreated | 2010-12-24 | lld:pubmed |
| pubmed-article:21129964 | pubmed:abstractText | High-throughput screening of 3.87 million compounds delivered a novel series of non-steroidal GR antagonists. Subsequent rounds of optimisation allowed progression from a non-selective ligand with a poor ADMET profile to an orally bioavailable, selective, stable, glucocorticoid receptor antagonist. | lld:pubmed |
| pubmed-article:21129964 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21129964 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21129964 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:21129964 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21129964 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:21129964 | pubmed:issn | 1464-3405 | lld:pubmed |
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| pubmed-article:21129964 | pubmed:copyrightInfo | Copyright © 2010. Published by Elsevier Ltd. | lld:pubmed |
| pubmed-article:21129964 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21129964 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:21129964 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:21129964 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21129964 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21129964 | pubmed:pagination | 137-40 | lld:pubmed |
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| pubmed-article:21129964 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21129964 | pubmed:articleTitle | Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist. | lld:pubmed |
| pubmed-article:21129964 | pubmed:affiliation | Merck Research Laboratories (MSD), Newhouse, Motherwell, Lanarkshire ML1 5SH, UK. angus.brown@merck.com | lld:pubmed |
| pubmed-article:21129964 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:21129964 | lld:chembl |
