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pubmed-article:2111437pubmed:abstractTextLarge deletion and small insertion mutations in the adenylyl cyclase gene of Saccharomyces cerevisiae were used to map regions required for activation by RAS protein in vitro. The amino-terminal 605 amino acids were found to be dispensable for responsiveness to RAS protein. All other deletions in adenylyl cyclase destroyed its ability to respond to RAS. Small insertion mutations within the leucine-rich repeat region also prevented RAS responsiveness, while other insertions did not.lld:pubmed
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pubmed-article:2111437pubmed:articleTitleMutational mapping of RAS-responsive domains of the Saccharomyces cerevisiae adenylyl cyclase.lld:pubmed
pubmed-article:2111437pubmed:affiliationCold Spring Harbor Laboratory, New York 11724.lld:pubmed
pubmed-article:2111437pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:2111437pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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