| pubmed-article:2109293 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0043210 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0018067 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0018061 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0205065 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0205228 | lld:lifeskim |
| pubmed-article:2109293 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:2109293 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2109293 | pubmed:dateCreated | 1990-5-18 | lld:pubmed |
| pubmed-article:2109293 | pubmed:abstractText | Failure to respond to human menopausal gonadotropin (hMG) with adequate ovarian stimulation is associated with a poor prognosis in subsequent cycles in women participating in an in vitro fertilization/embryo transfer program. Sera from 26 menstruating women (mean age 38 +/- 4.3 years) identified as "low responders" with either tubal or male factor infertility, mean baseline FSH values of 11 mIU/mL, and peak serum estradiol levels lower than 300 pg/mL were assessed for specific antibodies to human ovary and gonadotropins. Twenty-five infertile women with tubal or male factor infertility with a good response to hMG served as controls. Ninety-two percent of low responders had antibodies to FSH and 65% had antibodies to LH when assessed by enzyme-linked immunosorbent assay. Similarly, 77% of low responders had ovarian antibodies. No hepatic antibodies were found in the sera of low responders, indicating that the positivity was not a general interaction with cell components. None of the "good responders" had antibodies to gonadotropins or to ovarian or liver tissue. The significant differences in antibodies between the groups supports a possible immunologic cause for low ovarian stimulation response to gonadotropin. | lld:pubmed |
| pubmed-article:2109293 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2109293 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2109293 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2109293 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2109293 | pubmed:month | May | lld:pubmed |
| pubmed-article:2109293 | pubmed:issn | 0029-7844 | lld:pubmed |
| pubmed-article:2109293 | pubmed:author | pubmed-author:LuborskyJ LJL | lld:pubmed |
| pubmed-article:2109293 | pubmed:author | pubmed-author:DeCherneyA... | lld:pubmed |
| pubmed-article:2109293 | pubmed:author | pubmed-author:LavyGG | lld:pubmed |
| pubmed-article:2109293 | pubmed:author | pubmed-author:MeyerW RWR | lld:pubmed |
| pubmed-article:2109293 | pubmed:author | pubmed-author:VisintinII | lld:pubmed |
| pubmed-article:2109293 | pubmed:author | pubmed-author:EconomyKK | lld:pubmed |
| pubmed-article:2109293 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2109293 | pubmed:volume | 75 | lld:pubmed |
| pubmed-article:2109293 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2109293 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2109293 | pubmed:pagination | 795-9 | lld:pubmed |
| pubmed-article:2109293 | pubmed:dateRevised | 2009-10-26 | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
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| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:meshHeading | pubmed-meshheading:2109293-... | lld:pubmed |
| pubmed-article:2109293 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2109293 | pubmed:articleTitle | Evidence of gonadal and gonadotropin antibodies in women with a suboptimal ovarian response to exogenous gonadotropin. | lld:pubmed |
| pubmed-article:2109293 | pubmed:affiliation | Department of Obstetrics and Gynecology, Yale School of Medicine, New Haven, Connecticut. | lld:pubmed |
| pubmed-article:2109293 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2109293 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2109293 | lld:pubmed |
