The aim of this study was to evaluate the optimal preanalytical conditions prior to nucleic acid amplification technology (NAT) for human immunodeficiency virus-1 (HIV-1) or Hepatitis C virus (HCV) RNA in pools of 96 plasma specimens with regard to storage temperature, time and plasma separation in a blood donation environment.
Institute of Transfusion Medicine and Immunlogie, German Red Cross Blood Service, Baden Württemberg-Hessen, Medical Faculty of Mannheim, Heidelberg University, Mannheim, Germany.