| pubmed-article:21075690 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21075690 | lifeskim:mentions | umls-concept:C0231330 | lld:lifeskim |
| pubmed-article:21075690 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:21075690 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:21075690 | lifeskim:mentions | umls-concept:C0175630 | lld:lifeskim |
| pubmed-article:21075690 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:21075690 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21075690 | pubmed:dateCreated | 2011-1-17 | lld:pubmed |
| pubmed-article:21075690 | pubmed:abstractText | B cell gut-homing is mainly mediated by ?4?7, CCR9 and CCR10. We here studied the expression of these receptors on B cells from cord blood and from peripheral blood at 1, 4, 18 and 36 months of age in a prospective cohort of Swedish infants. The proportion of all B cells expressing ?4?7 as well as the fraction of CCR10+ B cells expressing ?4?7 was highest in early infancy. Nearly all naïve B cells in all age groups expressed ?4?7, whereas the expression on class-switched B cells decreased with age. Moreover, the proportion of both IgA+ and IgG+ B cells expressing ?4?7, CCR9 and CCR10 were higher during the first months when compared to adults. In conclusion, the high fraction of circulating IgA+ and IgG+ B cells expressing CCR9 and CCR10 in the first months of life indicates activation of naïve B cells in the gut, coinciding with bacterial colonization. | lld:pubmed |
| pubmed-article:21075690 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21075690 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075690 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21075690 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:21075690 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21075690 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21075690 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:21075690 | pubmed:issn | 1521-7035 | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:RudinAnnaA | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:AnderssonKers... | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:NordströmInge... | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:WoldAgnes EAE | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:AdlerberthIng... | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:Quiding-Järbr... | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:LundellAnna-C... | lld:pubmed |
| pubmed-article:21075690 | pubmed:author | pubmed-author:RabeHardisH | lld:pubmed |
| pubmed-article:21075690 | pubmed:copyrightInfo | Copyright © 2010 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:21075690 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21075690 | pubmed:volume | 138 | lld:pubmed |
| pubmed-article:21075690 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21075690 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21075690 | pubmed:pagination | 97-106 | lld:pubmed |
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| pubmed-article:21075690 | pubmed:meshHeading | pubmed-meshheading:21075690... | lld:pubmed |
| pubmed-article:21075690 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21075690 | pubmed:articleTitle | Development of gut-homing receptors on circulating B cells during infancy. | lld:pubmed |
| pubmed-article:21075690 | pubmed:affiliation | Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden. anna-carin.lundell@rheuma.gu.se | lld:pubmed |
| pubmed-article:21075690 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21075690 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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