| pubmed-article:21053160 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21053160 | lifeskim:mentions | umls-concept:C0024109 | lld:lifeskim |
| pubmed-article:21053160 | lifeskim:mentions | umls-concept:C1855355 | lld:lifeskim |
| pubmed-article:21053160 | lifeskim:mentions | umls-concept:C1506307 | lld:lifeskim |
| pubmed-article:21053160 | lifeskim:mentions | umls-concept:C0013081 | lld:lifeskim |
| pubmed-article:21053160 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:21053160 | pubmed:dateCreated | 2011-2-17 | lld:pubmed |
| pubmed-article:21053160 | pubmed:abstractText | Pulmonary hypoplasia is a primary cause of high morbidity and mortality in neonates with Congenital Diaphragmatic Hernia (CDH). However, the precise pathogenesis of PH associated with CDH is still not clearly understood. It has been recently reported that lung Kruppel-like factor (LKLF), a member of the Kruppel-like factor family of transcription factors, is predominantly expressed in lungs and plays an important role in lung morphogenesis and functional maturation. It has been reported that homozygous deletion of LKLF gene in mice results in reduced lung morphogenesis. It is further reported that chimeric mice derived from LKLF (-/-) embryonic stem cells exhibit delayed lung development especially in the later gestational stages. We therefore designed this study to test the hypothesis that the LKLF gene is down-regulated during later stages of lung development in nitrofen-induced hypoplastic lungs. | lld:pubmed |
| pubmed-article:21053160 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21053160 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21053160 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21053160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21053160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21053160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21053160 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21053160 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21053160 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:21053160 | pubmed:issn | 1439-359X | lld:pubmed |
| pubmed-article:21053160 | pubmed:author | pubmed-author:PuriPP | lld:pubmed |
| pubmed-article:21053160 | pubmed:author | pubmed-author:DoiTT | lld:pubmed |
| pubmed-article:21053160 | pubmed:author | pubmed-author:DingemannJJ | lld:pubmed |
| pubmed-article:21053160 | pubmed:author | pubmed-author:RuttenstockE... | lld:pubmed |
| pubmed-article:21053160 | pubmed:author | pubmed-author:Lukoši?t?AA | lld:pubmed |
| pubmed-article:21053160 | pubmed:copyrightInfo | © Georg Thieme Verlag KG Stuttgart · New York. | lld:pubmed |
| pubmed-article:21053160 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21053160 | pubmed:volume | 21 | lld:pubmed |
| pubmed-article:21053160 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21053160 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21053160 | pubmed:pagination | 38-41 | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:meshHeading | pubmed-meshheading:21053160... | lld:pubmed |
| pubmed-article:21053160 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21053160 | pubmed:articleTitle | Down-regulation of lung Kruppel-like factor in the nitrofen-induced hypoplastic lung. | lld:pubmed |
| pubmed-article:21053160 | pubmed:affiliation | National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland. | lld:pubmed |
| pubmed-article:21053160 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21053160 | pubmed:publicationType | Comparative Study | lld:pubmed |
| entrez-gene:306330 | entrezgene:pubmed | pubmed-article:21053160 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:21053160 | lld:entrezgene |
