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pubmed-article:20981219rdf:typepubmed:Citationlld:pubmed
pubmed-article:20981219lifeskim:mentionsumls-concept:C0019169lld:lifeskim
pubmed-article:20981219lifeskim:mentionsumls-concept:C0030705lld:lifeskim
pubmed-article:20981219lifeskim:mentionsumls-concept:C0087111lld:lifeskim
pubmed-article:20981219lifeskim:mentionsumls-concept:C0015624lld:lifeskim
pubmed-article:20981219lifeskim:mentionsumls-concept:C0332281lld:lifeskim
pubmed-article:20981219lifeskim:mentionsumls-concept:C0540694lld:lifeskim
pubmed-article:20981219lifeskim:mentionsumls-concept:C0439590lld:lifeskim
pubmed-article:20981219pubmed:issue3lld:pubmed
pubmed-article:20981219pubmed:dateCreated2010-10-28lld:pubmed
pubmed-article:20981219pubmed:abstractTextAdefovir dipivoxil (ADV) is commonly used as an antiviral agent in the treatment of chronic hepatitis B or human immunodeficiency virus infection. Nephrotoxicity has been shown to occur at daily dosages of 60-120 mg. Fanconi's syndrome is a generalized dysfunction of the renal proximal tubular cells, which is usually accompanied by complications. Here we report a case of Fanconi's syndrome in a chronic hepatitis B patient who had been treated with a prolonged regimen of ADV at 10 mg/day. A 47-year-old man complained of severe back and chest-wall pain. He had chronic hepatitis B and had been treated with ADV at a daily dose of 10 mg for 38 months. He was hospitalized because of severe bone pain, and laboratory and radiologic findings suggested a diagnosis of Fanconi's syndrome with osteomalacia. After discontinuation of the ADV, he recovered and was discharged from hospital. His laboratory findings had normalized within 2 weeks. This case indicates that Fanconi's syndrome can be acquired by a chronic hepatitis B patient taking ADV at a conventional dosage of 10 mg/day. Therefore, patients treated with long-term ADV should be checked regularly for the occurrence of ADV-induced Fanconi's syndrome.lld:pubmed
pubmed-article:20981219pubmed:languageenglld:pubmed
pubmed-article:20981219pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:20981219pubmed:statusPubMed-not-MEDLINElld:pubmed
pubmed-article:20981219pubmed:monthSeplld:pubmed
pubmed-article:20981219pubmed:issn1976-2283lld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:ParkJong...lld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:KimJi HoonJHlld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:KimJae SeonJSlld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:YeonJong...lld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:ByunKwan...lld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:BakYoung-TaeY...lld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:KimChung HoCHlld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:JungEun SukESlld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:JungYoung...lld:pubmed
pubmed-article:20981219pubmed:authorpubmed-author:ChoiJong...lld:pubmed
pubmed-article:20981219pubmed:issnTypePrintlld:pubmed
pubmed-article:20981219pubmed:volume4lld:pubmed
pubmed-article:20981219pubmed:ownerNLMlld:pubmed
pubmed-article:20981219pubmed:authorsCompleteYlld:pubmed
pubmed-article:20981219pubmed:pagination389-93lld:pubmed
pubmed-article:20981219pubmed:year2010lld:pubmed
pubmed-article:20981219pubmed:articleTitleFanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient.lld:pubmed
pubmed-article:20981219pubmed:affiliationDepartment of Internal Medicine, Gachon University of Medicine and Science Gil Medical Center, Incheon, Korea.lld:pubmed
pubmed-article:20981219pubmed:publicationTypeJournal Articlelld:pubmed