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pubmed-article:20947926pubmed:abstractTextOwing to its peculiar pharmacological characteristics, paclitaxel attains substantial intra-peritoneal concentration for a prolonged period when delivered intra-peritoneally, and is active against peritoneal metastasis of ovarian cancer. It is also considered promising against disseminated gastric cancer. However, the fact that the intra-peritoneal paclitaxel has not been approved in Japan has rendered its evaluation by a formal clinical trial impossible. The authors designed a randomized phase II trial using the Kodo Iryo Hyoka system, a new system to legally test an yet unapproved mode of treatment. It is hoped that this trial will result in a breakthrough in the treatment of peritoneal carcinomatosis from gastric cancer.lld:pubmed
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pubmed-article:20947926pubmed:authorpubmed-author:NakaoAkimasaAlld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:KoderaYasuhir...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:TakahashiNaot...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:SasakoMitsuru...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:SakamotoJunic...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:YoshikawaTaka...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:TsuburayaAkir...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:MoritaSatoshi...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:ImanoMotohiro...lld:pubmed
pubmed-article:20947926pubmed:authorpubmed-author:MiyashitaYumi...lld:pubmed
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pubmed-article:20947926pubmed:volume41lld:pubmed
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pubmed-article:20947926pubmed:pagination283-6lld:pubmed
pubmed-article:20947926pubmed:dateRevised2011-4-20lld:pubmed
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pubmed-article:20947926pubmed:year2011lld:pubmed
pubmed-article:20947926pubmed:articleTitleA randomized phase II trial to test the efficacy of intra-peritoneal paclitaxel for gastric cancer with high risk for the peritoneal metastasis (INPACT trial).lld:pubmed
pubmed-article:20947926pubmed:affiliationDepartment of Surgery II, Nagoya University Graduate School of Medicine, 63 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. ykodera@med.nagoya-u.ac.jplld:pubmed
pubmed-article:20947926pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:20947926pubmed:publicationTypeRandomized Controlled Triallld:pubmed
pubmed-article:20947926pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:20947926pubmed:publicationTypeMulticenter Studylld:pubmed
pubmed-article:20947926pubmed:publicationTypeClinical Trial, Phase IIlld:pubmed