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pubmed-article:20919552pubmed:abstractTextAfobazole and M-11, its major metabolite were detected in placental and embryonic rat tissues after single peroral administration to pregnant female rats at a dose of 100 mg/kg. The anxiolytic drug and its metabolite are also detected in rat milk and body of the breast-fed infant rat pups after 4 days of daily administration (200 mg/kg, per os) to lactating female rats.lld:pubmed
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pubmed-article:20919552pubmed:articleTitle[Model study of afobazole distribution in pregnant and lactating female rats and infant rat pups].lld:pubmed
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